F. Hoffmann La Roche and Johnson & Johnson license patented drug-discovery platform technologies from Housey Pharma
SOUTHFIELD, Mich., Aug. 11, 2020 /PRNewswire-PRWeb/ -- Both Roche, based in Basel, Switzerland, and J&J's Janssen R&D subsidiary based in Princeton, NJ, have entered into license agreements with Housey Pharma's HMI subsidiary to gain access to its core-enabling technology for new-drug discovery and development. Both Roche and J&J have annual Research and Development spending in excess of US $10 billion.
Scientists at Housey Pharma have developed the next generation of drug-discovery technology in the
cell-based assay field. The Company's technologies are being offered for licensure on a non-exclusive basis to other research-based pharmaceutical companies worldwide. Cell-based assay systems are research tools that use living cells to identify and refine new medicines.
According to Dr. Housey, one of the co-inventors of the technology, the platform enables the creation of
target-specific, cell-based assay systems through specific technologies in genetic engineering, biochemistry and cell-biology. It is especially well-suited to targets previously thought to be "undruggable" in the human genome. Undruggable targets is a term used in the pharmaceutical industry to refer to biomolecules for which it was previously believed to be impossible to create a medicine capable of altering the biological function of the human body in a therapeutically beneficial manner.
"Housey Pharma has developed a technology platform to create effective medicines for the undruggable targets that are found in many human diseases, such as drug-resistant cancers, diabetes, neurodegenerative disorders such as dementia, and many other disease states," said Dr. Housey.
The licensed drug-discovery platform technology has been awarded nine patents in the United States and dozens of other countries worldwide, with many more pending. The technology includes methods of discovering compounds that overcome drug-resistant cancers, generalized drug discovery and lead-optimization methods applicable to all human diseases, and certain compounds. The technology is particularly applicable to the discovery and development of protein kinase inhibitors useful for the treatment of drug-resistant cancers.
"Breakthroughs in the discovery and development of new medicines are enabled through the use of this advanced technology platform," said Dr. Housey. "We look forward to seeing innovative new medicines that benefit people around the world brought forth by our scientific colleagues at Roche and J&J. These companies have been at the forefront of innovations in medicine ranging from new treatments in oncology to COVID-19 vaccines."
About Housey Pharma
Housey Pharma is a commercial-stage, privately held biopharmaceutical company engaged in the discovery, research, development and sale of medicines that address important, unserved medical and health needs. Housey Pharma's products are created through the application of advanced, patented and proprietary drug discovery technologies invented by Housey Pharma. The company believes its patented technologies comprise a core-enabling technology platform that provides it with a competitive advantage for new drug discovery and creation.
Housey Pharma plans to launch a Phase 2 clinical program on one of its anti-diabetic medications in 2021. This first-in-class botanical compound targets the Insulin Receptor Substrate-2 (IRS2) pathway in human cells. IRS-2 is a protein previously considered to be an "undruggable" target. Housey Pharma has also developed the world's first orally active compound that directly targets the same pathway that insulin uses to stimulate human cells to remove glucose (sugar) from the bloodstream. Housey Pharma's compounds enhance insulin action in such a way that little or no insulin is needed to keep blood sugar under control. For more information, visit http://www.housey.com.
MEDIA CONTACT: Jeff Caponigro, jcap@caponigro.com, (248) 388-4981
SOURCE Housey Pharmaceutical Research Laboratories, LLC
