Cytomegalovirus Infection Treatment Market elevates at a CAGR of 13.79% during 2020-2030, asserts DelveInsight
LAS VEGAS, Jan. 27, 2021 /PRNewswire/ -- DelveInsight's "Cytomegalovirus (CMV) Infection Market Report" report provides an absolute comprehension of the Cytomegalovirus Infection, historical and forecasted epidemiology and the CMV market trends in the 7MM [the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan]. The Cytomegalovirus market report also proffers an analysis of recent Cytomegalovirus treatment practice/algorithm, market drivers, market barriers and unmet medical needs.
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Some of the essential highlights of the Cytomegalovirus Therapeutics Market Research Report :
-- Increasing CMV Infections cases in various regions leads to increased
demand for advanced diagnostics that, in turn, contribute to the CMV
market growth.
-- The Cytomegalovirus Infection treatment market is divided into
Prophylaxis and Therapeutic. Currently, the market is dominated by drugs
like valganciclovir, valacyclovir hydrochloride, and others. However,
the CMV market of these drugs will experience a plunge in market share
due to the launch of new emerging therapies.
-- Cytomegalovirus Therapeutics Market anticipates the emergence of
pipeline products namely V160 (Merck), mRNA-1647 (ModernaTX),
HB-101/VaxWave (Hookipa Biotech), Triplex (Helocyte), Maribavir
(TAK-602) (Takeda/Shire Pharmaceuticals), and Viralym-M (AlloVir).
-- One of the most promising anti-CMV drugs in clinical development is
Maribavir (Shire). The drug is in phase III stage of development for the
transplant cases with Cytomegalovirus Infections that are refractory or
treatment-resistant, and also, for Cytomegalovirus (CMV) Infection
Treatment in Hematopoietic Stem Cell Transplant Recipients.
For additional information on Market Impact by Therapies, visit: Global Cytomegalovirus Treatment Market Report
Cytomegalovirus (CMV) Infection is a viral infection that rarely causes serious illness. Human CMV causes a broad variety of infection and illness in healthy adults, in those with compromised immune systems (such as AIDS), in those with cardiovascular disease, and in pregnant women who can pass the infection to their unborn child (congenital CMV). In 2020, the total of Cytomegalovirus diagnosed cases were found to be 111,959 cases in the 7MM.
The Cytomegalovirus Infection Market Report provides historical as well as forecasted epidemiological analysis segmented into:
-- Total Diagnosed Cases of CMV Infection
-- Number of Infants born with Congenital CMV
-- CMV Patients among Hematopoietic Stem Cell Transplants (HSCT)
-- Number of CMV Patients among Solid Organ Transplantation (SOT)
-- Number of Refractory CMV Patients after HSCT/SOT
-- CMV Retinitis among HIV Patients
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Cytomegalovirus Infection Therapeutics Market Analysis
The management of CMV infection is maintained by two approaches, i.e. prophylaxis and therapeutic approach. Currently, the global Cytomegalovirus treatment market is dominated by drugs like valganciclovir, valacyclovir hydrochloride, and others. However, the market of these drugs will experience a drop in the market share due to the launch of new emerging therapies. Recently, Prevymis (Letermovir) received FDA approval in 2017, to prevent Human Cytomegalovirus (HCMV) infection in transplant patients and entered the market in 2018. Prevymis covers a tiny targeted population because it is approved only for the prophylaxis of cytomegalovirus (CMV) reactivation and disease in adult CMV-seropositive recipients [R+] of an allogeneic hematopoietic stem cell transplant (HSCT).
Hence, it will positively impact the market size growth but will not be responsible for the major increase in the CMV market size. There is an estimated decline in its market after 2029, as the patent of prevymis will expire in 2029. Among the prophylactic potential market, two therapies, V160 and mRNA-1647, target the same patient population, CMV-seronegative and CMV-seropositive healthy adults (childbearing women) to prevent congenital CMV. Moreover, in the therapeutic potential market, it is believed that Maribavir can be a promising agent in the US for Cytomegalovirus Infection treatment.
In the United States, antiviral drugs are used for CMV infection following transplant procedures. The drugs include valganciclovir, ganciclovir, cidofovir, foscarnet, or a combination. The US FDA and EMA support the CMV therapeutics pipeline by encouraging the drug development process through a different type of designations.
Cytomegalovirus Infection Emerging Products Along with Key Players
-- Maribavir (TAK-602): Takeda/Shire Pharmaceuticals
-- ATA230: Atara Biotherapeutics
-- Triplex: Helocyte
-- Viralym-M: AlloVir
-- V160: Merck
-- VBI-1501: VBI Vaccines
-- HB-101 (VaxWave): Hookipa Biotech
-- AVX601: AlphaVax
-- CMV glycoprotein B MF59 (gB/MF59): Sanofi
-- ALVAC-CMV (vCP260): Sanofi
-- NPC-21: Nobelpharma
-- mRNA-1647: ModernaTX
-- VBI-1901: VBI Vaccines
-- ITI-1001: Immunomic Therapeutics
And several others.
Concluding Thoughts on CMV Therapeutics Market Growth
CMV Market Drivers are attributable to
-- Emerging Therapies- The high burden of CMV disease and morbidity makes
it a right candidate for new therapies and vaccines.
-- Better Efficacy and Safety Profiles - Various pipeline molecules show
better safety and promising activity than those currently being used.
-- Increased incidence and prevalence - Increased public awareness creates
a lucrative opportunity for innovation of therapeutics.
-- Increased awareness - Growing R&D is increasing the demand for better
diagnosis and CMV Infections treatment options.
However, there are CMV Market size growth Barriers that influence CMV Market growth
-- Challenges in existing therapies- Current therapies are inadequate
because of severe toxicities.
-- Diagnostic challenges in congenital cytomegalovirus infection-
Diagnostic options are much needed to improve the CMV prognosis and
outcomes for patients, as existing diagnostic options do not detect some
features of congenital CMV.
-- Generic drugs of off-patent therapies- All available drugs for CMV
infection have gone off-patented except one. The generic market of a
drug shall affect the overall sales of the CMV market.
-- The complex mechanism of action and treatment costs- There is a lack of
knowledge about the complex mechanism of action of the disease with
various targets for inhibition.
-- Limitation in the current therapeutic market - One of the major unmet
needs primarily in the prophylactic market is the efficacy and the viral
resistance to the current drugs that is a limitation for the current
therapeutic market.
Scope of the Cytomegalovirus Infection Market
-- Geography Covered: 7MM - The United States, EU5 (Germany, France, Italy,
Spain, and the United Kingdom), Japan.
-- Study Period: 3-year historical and 11-year forecasted analysis
(2017-2030).
-- Cytomegalovirus Infection Markets Segmentation: By Geographies and By
Cytomegalovirus Infection Therapies (Historical and Forecasted, Current
and Upcoming)
-- Leading Companies investigating its candidates for CMV Infections:
Takeda/Shire Pharmaceuticals, Atara Biotherapeutics, Helocyte, AlloVir,
Merck, VBI Vaccines, Hookipa Biotech, AlphaVax, Sanofi, Nobelpharma,
ModernaTX, Immunomic Therapeutics, and several others.
-- Analysis: Comparative and conjoint analysis of emerging therapies,
Attribute Analysis.
-- Case Studies
-- KOL's Views
-- Analyst's View
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Table of Contents
1
Key Insights
---
2 Executive Summary of Cytomegalovirus
Infection
---
3 Cytomegalovirus Infection Market Overview
at a Glance
---
4 Disease Background and Overview:
Cytomegalovirus Infection (CMV)
---
5 Case Reports of Cytomegalovirus Infection
---
6 Cytomegalovirus Infection Patient Journey
---
7 CMV Epidemiology and Patient Population
---
8 Country Wise-Epidemiology of CMV
Infections
---
8.1
United States
---
8.2
EU5 Countries
---
8.2.1
Germany
---
8.2.2
France
---
8.2.3
Italy
---
8.2.4
Spain
---
8.2.5
United Kingdom
---
8.3
Japan
---
9 Cytomegalovirus Infection Treatment
Algorithm
---
10 Cytomegalovirus Infection Unmet Needs
---
11 Cytomegalovirus Infection Marketed Products
---
11.1
Valcyte: Roche
---
11.2
Foscavir: Clinigen Group plc
---
11.3
CytoGam: CSL Behring
---
11.4
Valtrex: GlaxoSmithKline
---
11.5
Vistide: Gilead Sciences
---
11.6
Prevymis: Merck & Co.
---
11.7
Cytotect CP: Biotest Pharma GmbH
---
12 Cytomegalovirus Infection Emerging Drugs
---
12.1
Key Cross Competition
---
12.2
CMV-Gyn (Cytotect 70): Biotest AG
---
12.3 Maribavir (TAK-602): Takeda/Shire
Pharmaceuticals
---
12.4
ATA230: Atara Biotherapeutics
---
12.5
Triplex: Helocyte
---
12.6
Viralym-M: AlloVir
---
12.7
V160: Merck
---
12.8
VBI-1501: VBI Vaccines
---
12.9
HB-101 (VaxWave): Hookipa Biotech
---
12.10
AVX601: AlphaVax
---
12.11 CMV glycoprotein B MF59 (gB/MF59): Sanofi
---
12.12
ALVAC-CMV (vCP260): Sanofi
---
12.13
NPC-21: Nobelpharma
---
12.14
mRNA-1647: ModernaTX
---
12.15
VBI-1901: VBI Vaccines
---
12.16
ITI-1001: Immunomic Therapeutics
---
13
CMV Failed Therapies
---
13.1 ASP0113: Astellas Pharma Global
Development, Inc.
---
13.2
Brincidofovir: Chimerix Inc.
---
13.3 CSJ148: Novartis (Development suspended)
---
14 Cytomegalovirus Infection 7MM Analysis
---
15 CMV Attribute Analysis of Prophylactic
Drugs
---
16 Cytomegalovirus Infection Attribute
Analysis of Therapeutic Drugs
---
17 Key Market Forecast Assumptions
---
18 The United States Cytomegalovirus Infection
Market Outlook
---
19 EU-5 Countries CMV Market Outlook
---
19.1
Germany Market Size
---
19.2
France Market Size
---
19.3
Italy Market Size
---
19.4
Spain Market Size
---
19.5
United Kingdom Market Size
---
20 Japan Cytomegalovirus Infection Market
Outlook
---
21 Cytomegalovirus Infection Market Drivers
---
22
CMV Market Barriers
---
23 Cytomegalovirus Infection SWOT Analysis
---
24 Reimbursement and CMV Market Access
---
25 Recognized Establishments
---
26
Appendix
---
27 DelveInsight Capabilities
---
28
Disclaimer
---
29
About DelveInsight
---
Browse detailed TOC with charts, figures, tables @ Cytomegalovirus Infection Market Size Report
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