Embryo Transfer following Screening, Freezing, and Thawing shown to be more successful than Fresh Transfer of Screened Embryos
NEW YORK, Nov. 3, 2017 /PRNewswire/ -- In a study focused on optimizing euploid embryo transfers, the Manhattan-based fertility center Reproductive Medicine Associates of New York (RMA of NY, www.rmany.com) joined 12 private and academic fertility centers in the United States to compare the impact of transferring fresh versus frozen screened embryos. The research was one of 33 scientific abstracts presented by RMA of NY at the 73nd annual meeting of the American Society of Reproductive Medicine (ASRM, www.asrm.com) in San Antonio, Texas.
Dr. Alan B. Copperman, Co-Director of RMA of NY and Vice Chairman of Obstetrics and Gynecology and Director of the Division of Reproductive Endocrinology and Infertility at the Icahn School of Medicine at Mount Sinai Hospital in New York, explains:
"Optimal care of the infertile couple involves compassion, science, and data-driven decisions. With the advent of next generation sequencing of embryos, the likelihood of conception from infertility treatment has improved markedly. Despite early concerns that success would be hindered by freezing and thawing embryos, in this large multi-center study we demonstrated that transfer of a thawed embryo actually improves success rates and patient outcomes."
Employing the use of high-powered statistics with the use of generalized estimating equations modeling the groups analyzed 1,642 matched blastocyst transfer cycles, with 821 freeze-all transfer cycles and 821 fresh transfer cycles.
The study identified patients who transferred an euploid embryo after a freeze-all cycle enhanced their cycle's ongoing pregnancy rates, a near 11% leap from patients who pursued a fresh transfers (53.1% vs. 42.6% p<0.0001). This significant finding suggests patients who want to optimize their chances of having an ongoing pregnancy to consider a freeze-all transfer cycle. Also, the study's finding did not waiver by patient's age or the amount of progesterone administered during the cycle.
Lead author, Dr. Ange Wang, a resident physician in obstetrics and gynecology at Stanford University School of Medicine, added:
"To our knowledge, this is the largest study to date to compare optimal transfer of euploid embryos in fresh transfer cycles versus freeze-only cycles. Our findings are potentially valuable to reproductive practitioners and patients to help inform decision making in IVF cycles. This study also gives support towards leveraging big data to positively influence the decision making processes of clinical care."
Given the advances in vitrification and innovations in genetic screening platforms, patients now routinely choose to have their embryos biopsied and analyzed and benefit from improved implantation and delivery rates.
Press interviews with RMA of New York can be arranged through Allysa Mizerek, Director of Marketing (212-756-5777), amizerek@rmany.com.
About Reproductive Medicine Associates of New York, LLP
Reproductive Medicine Associates of New York (RMA of NY) is a global leader in delivering personalized, precise, and compassionate reproductive care. The integrated team of physicians and scientists at RMA of NY has extensive experience and training in reproductive endocrinology, fertility, and urology, and consistently reports high success rates to the Society for Assisted Reproductive Technology (SART) and the Centers for Disease Control and Prevention (CDC). As part of the Icahn School of Medicine at Mount Sinai, RMA of NY performs scientific, educational, and clinical functions. RMA of NY has been recognized as a leader in LGBTQ reproductive care, for women choosing single or same-sex motherhood, and for women and men pursuing fertility preservation for elective and medical indications.
Headquartered in Midtown Manhattan, RMA of NY has three patient care facilities in Manhattan, as well as offices in Brooklyn, Garden City, and White Plains, NY. Additionally, RMA of NY has patient care facilities in Mexico City, Mexico. For more information, visit www.rmany.com.
Media Contact: Allysa Mizerek, Reproductive Medicine Associates of New York, 212-756-5777, amizerek@rmany.com
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SOURCE Reproductive Medicine Associates of New York
