Genomic Health Announces Record Revenue and Profit in Third Quarter 2018 Financial Results; Raises Full Year Guidance

REDWOOD CITY, Calif., Nov. 6, 2018 /PRNewswire/ -- Genomic Health, Inc. (NASDAQ: GHDX) today reported financial results and business progress for the quarter ended September 30, 2018.

"We continue to deliver record results in 2018, including 23 percent revenue growth and $12 million in profit for the third quarter. Our strong performance this year reflects increasing global demand and revenue for the Oncotype DX Breast Recurrence Score test, continued demand and growing reimbursement for the Genomic Prostate Score test and success in driving operational efficiencies across the business," said Kim Popovits, chairman of the board, chief executive officer and president of Genomic Health. "With three quarters of record performance this year, we are raising our full year 2018 guidance and expect to deliver more than 17 percent revenue growth for the year."

Third Quarter and Nine Months Ended September 30, 2018, Financial Results
Total revenue was $101.3 million in the third quarter of 2018, compared with pre-606 adjusted revenue* of $82.2 million for the third quarter of 2017, an increase of 23 percent. Reported revenue was $83.8 million in the third quarter of 2017.

U.S. product revenue was $85.8 million in the third quarter of 2018, compared with pre-606 adjusted revenue of $69.5 million for the third quarter of 2017, an increase of 23 percent. U.S. product reported revenue was $70.9 million in the third quarter of 2017. U.S. invasive breast revenue from Oncotype DX Breast Recurrence Score(®) tests was $76.7 million in the third quarter of 2018, compared with U.S. invasive breast pre-606 adjusted revenue of $61.6 million for the third quarter of 2017, an increase of 24 percent. U.S. invasive breast reported revenue was $63.1 million in the third quarter of 2017. U.S. prostate test revenue from Oncotype DX(®) Genomic Prostate Score(® )(GPS(TM)) tests was $6.9 million in the third quarter of 2018, compared with $5.4 million in the third quarter of 2017, an increase of 28 percent.

International product revenue was $15.5 million in the third quarter of 2018, compared with pre-606 adjusted revenue of $12.7 million for the third quarter of 2017, an increase of 22 percent, and a 20 percent increase on a non-GAAP constant currency basis. International product reported revenue was $12.9 million in the third quarter of 2017.

Net income was $12.2 million, or $0.34 and $0.32 per share on a basic and diluted basis, respectively, in the third quarter of 2018, an improvement of $14.4 million, compared with a net loss of $2.2 million, or $0.06 per share on a basic and diluted basis, in the third quarter of 2017. Operating income was $11.8 million in the third quarter of 2018, an improvement of $14.4 million, compared with an operating loss of $2.6 million in the third quarter of 2017.

On a non-GAAP basis, net income was $13.3 million in the third quarter of 2018, compared with a non-GAAP net income of $1.1 million in the third quarter of 2017. Non-GAAP operating income was $12.9 million in the third quarter of 2018, compared with a non-GAAP operating income of $0.6 million in the third quarter of 2017.

More than 34,810 Oncotype(TM) test results were delivered in the third quarter of 2018, an increase of 10 percent, compared with more than 31,580 test results delivered in the same period in 2017. Oncotype DX Breast Recurrence Score tests delivered in the U.S. grew 12 percent in the third quarter of 2018, compared with the same period in 2017. Oncotype DX GPS tests delivered in the U.S. grew 15 percent in the third quarter of 2018, compared with the same period in 2017. The number of international tests delivered grew 6 percent in the third quarter of 2018, compared with the same period in 2017 and represented approximately 25 percent of total test volume in the quarter.

Total revenue for the nine months ended September 30, 2018, was $289.5 million, compared with pre-606 adjusted revenue of $248.2 million for the same period in 2017, an increase of 17 percent, and an increase of 16 percent on a non-GAAP constant currency basis. Reported revenue was $253.3 million for the nine months ended September 30, 2017.

International product revenue was $43.4 million for the nine months ended September 30, 2018, compared with pre-606 adjusted revenue of $38.6 million for the nine months ended September 30, 2017, an increase of 12 percent, and a 9 percent increase on a non-GAAP constant currency basis. International product reported revenue was $39.4 million for the nine months ended September 30, 2017.

GAAP net income was $16.8 million for the nine months ended September 30, 2018, an improvement of $22.5 million, compared with a net loss of $5.7 million for the nine months ended September 30, 2017. Operating income increased to $14.5 million for the nine months ended September 30, 2018, an improvement of $23.1 million, compared with an operating loss of $8.6 million for the nine months ended September 30, 2017.

Non-GAAP net income was $27.3 million for the nine months ended September 30, 2018, compared with a $4.5 million non-GAAP net loss for the nine months ended September 30, 2017. Non-GAAP operating income was $26.5 million for the nine months ended September 30, 2018, compared with a non-GAAP operating loss of $5.4 million for the same period in 2017.

Cash and cash equivalents and short-term marketable securities at September 30, 2018 were $183.3 million, which included the fair value of the company's investment in marketable securities of $3.8 million, compared with $129.6 million at December 31, 2017, which included the fair value of the company's investment in marketable securities of $3.5 million.

2018 Financial Outlook
"We are on track to deliver revenue growth of 17 percent in 2018, surpassing both the top-end of our original revenue guidance for the full year and our annual revenue growth goal of 15 percent," said Brad Cole, chief financial officer of Genomic Health. "We are raising our revenue and net income guidance for the full year ending December 31, 2018, which assumes 17 to 19 percent year-over-year revenue growth in the fourth quarter and our 14(th) consecutive quarter of improved non-GAAP profitability."

Below is a table summarizing the 2018 full-year guidance revisions:


                  Updated Guidance Former Guidance



                
            Low                       
     High     
     Low        
     High



     Revenue(1)               $389                       $391         $366          $382


      Revenue
      Growth(2)                17%                       17%         10%          15%




      Net
      Income
      (GAAP)
      (1)                     $26                        $28           $0            $5


      GAAP
      Basic
      EPS
      (3)                   $0.72                      $0.78        $0.00         $0.14




      Net
      Income
      (Non-
      GAAP)
      (1)
      (4)                     $37                        $39          $14           $20


      Non-
      GAAP
      Basic
      EPS
      (3)                   $1.03                      $1.08        $0.39         $0.56


              (1)              In millions.



              (2)              The outlook
                                  for revenue
                                  growth in
                                  2018
                                  represents
                                  management's
                                  estimates for
                                  2018 versus
                                  2017 reported
                                  revenues
                                  adjusted to
                                  reflect the
                                  impact of ASC
                                  606 revenue
                                  recognition
                                  rules, which
                                  were
                                  effective
                                  January 1,
                                  2018. Under
                                  the new
                                  rules, the
                                  company will
                                  report most
                                  uncollectible
                                  balances as a
                                  reduction in
                                  net revenues;
                                  historically,
                                  certain
                                  uncollectible
                                  amounts were
                                  classified as
                                  bad debt
                                  expense and
                                  were
                                  approximately
                                  2.5% of
                                  revenue and
                                  classified
                                  within
                                  selling,
                                  general and
                                  administrative
                                  expenses. The
                                  company does
                                  not expect
                                  ASC 606 to
                                  impact net
                                  income or
                                  EPS.



              (3)              Based on 36
                                  million
                                  estimated
                                  shares
                                  outstanding.



              (4)              Non-GAAP net
                                  income
                                  exclusions,
                                  see "Non-
                                  GAAP
                                  Disclosure"
                                  paragraph in
                                  press release
                                  below.

Recent Business Highlights

    --  The National Comprehensive Cancer Network (NCCN) elevated the Oncotype
        DX Breast Recurrence Score to its "preferred" category as the only
        multi-gene test to predict chemotherapy treatment benefit for patients
        with node-negative early-stage breast cancer in its 2018 breast cancer
        guidelines.
    --  The German Institute for Quality and Efficiency in Health Care (IQWiG)
        concluded that "only the Oncotype DX Breast Recurrence Score test has
        sufficient evidence to guide breast cancer adjuvant chemotherapy
        decisions based on TAILORx study results" in its updated assessment of
        breast cancer gene expression profiling tests.
    --  Nature Partner Journals Breast Cancer published a systematic review of
        seven studies including more than 8,000 patients with node-positive
        breast cancer, confirming that the Oncotype DX test accurately predicts
        clinical outcomes in node-positive breast cancer.
    --  Palmetto GBA, a Medicare Administrative Contractor that assesses
        molecular diagnostic technologies, issued a positive final local
        coverage determination (LCD) for the Oncotype DX(®) AR-V7 Nucleus
        Detect(TM) test for qualified Medicare patients throughout the U.S.,
        effective in December 2018.
    --  Established new reimbursement for the Oncotype DX Genomic Prostate Score
        test with Blue Shield California, bringing the total number of U.S.
        covered lives to more than 100 million, including Medicare.
    --  Reviews in Urology published real-world clinical evidence demonstrating
        that Oncotype DX Genomic Prostate Score testing resulted in
        significantly higher use of active surveillance compared to no testing.
    --  An independent study published by University of California, San
        Francisco (UCSF) researchers in the Journal of Urology demonstrated that
        the Oncotype DX GPS test was predictive of an increased risk of biopsy
        upgrade in men with clinically low-risk prostate cancer managed by
        active surveillance.
    --  Presented results from five studies at the ESMO 2018 Congress
        reinforcing the utility of Oncotype DX tests in optimizing treatment for
        patients with various stages of breast and prostate cancer.
    --  Received acceptance to present two studies at the 2018 San Antonio
        Breast Cancer Symposium (SABCS) in December.

*Pre-606 Adjusted Product Revenue
Effective January 1, 2018, the company adopted the new ASC 606 accounting standard for revenue, using the modified retrospective method, which applies the new standard prospectively and does not impact prior years' financial statements. Since the as-reported 2017 quarterly and annual financial statements will not be restated to reflect the new accounting standard, the company has provided a supplemental financial schedule in the non-GAAP tables at the end of this press release, reflecting an estimate of revenue as if the new standard had been applied to the historical 2017 product revenue portion of revenue as of January 1, 2017, referred to herein as "pre-606 adjusted revenue."

Non-GAAP Disclosure
The company makes reference in this press release to "non-GAAP operating income (loss)," which excludes 2018 expenses resulting from the restructuring charges for the cessation of the Oncotype SEQ(®) Liquid Select(TM) test product development and commercialization activities in the first quarter of 2018, the cessation of its collaboration with Cleveland Diagnostics in the second quarter of 2018, and the expenses for milestone payments to Biocartis N.V., in the second and third quarters of 2018. Additionally, the company references "non-GAAP net income (loss)," which also excludes fair value adjustments related to its collaborations with Biocartis and Epic Sciences, and the gain on sale of marketable securities in the first quarter of 2017. The company believes that excluding these items and their related tax effects from its financial results reflects operating results that are more indicative of the company's ongoing operating performance while improving comparability to prior periods, and, as such, may provide investors with an enhanced understanding of the company's past financial performance and prospects for the future. The company also considers the impact of foreign currency exchange rates on its global business as described in the constant currency table accompanying this press release. The company's management uses such non-GAAP measures internally to evaluate and assess its core operations and to make ongoing operating decisions. This information is not intended to be considered in isolation or as a substitute for income (loss) from operations or net income (loss) information prepared in accordance with GAAP. An explanation and reconciliation of the non-GAAP financial measures to the most directly comparable GAAP financial measures is included in the tables accompanying this press release.

Conference Call Details
To access the live conference call today, November 6, at 4:30 p.m. Eastern Time via phone, please dial (877) 303-7208 from the United States and Canada, or +1 (224) 357-2389 internationally. The conference call ID is 9448559. Please dial in approximately ten minutes prior to the start of the call. To access the live and subsequently archived webcast of the conference call, go to the Investor Relations section of the company's website at http://investor.genomichealth.com. Please connect to the website at least 15 minutes prior to the presentation to allow for any software download that may be necessary.

About Genomic Health
Genomic Health
, Inc. (NASDAQ: GHDX) is the world's leading provider of genomic-based diagnostic tests that help optimize cancer care, including addressing the overtreatment of the disease, one of the greatest issues in healthcare today. With its Oncotype IQ(®) Genomic Intelligence Platform, the company is applying its world-class scientific and commercial expertise and infrastructure to lead the translation of clinical and genomic big data into actionable results for treatment planning throughout the cancer patient journey, from diagnosis to treatment selection and monitoring. The Oncotype IQ portfolio of genomic tests and services currently consists of the company's flagship line of Oncotype DX(®) gene expression tests that have been used to guide treatment decisions for more than 950,000 cancer patients worldwide. Genomic Health is expanding its test portfolio to include additional liquid- and tissue-based tests, including the recently launched Oncotype DX(®) AR-V7 Nucleus Detect(TM) test. The company is based in Redwood City, California, with international headquarters in Geneva, Switzerland. For more information, please visit www.GenomicHealth.com and follow the company on Twitter: @GenomicHealth, Facebook, YouTube and LinkedIn.

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including statements relating to the company's beliefs regarding its future performance, including updated 2018 guidance, the company's beliefs regarding its revenue growth for the remainder of 2018 and the drivers of growth; the commercial performance of its tests; the favorable impact of TAILORx results on revenue in 2018; the attributes and focus of the company's product pipeline; the ability of any potential tests the company may develop to optimize cancer treatment; the ability of the company to develop and commercialize and collaborate with third parties to commercialize additional tests in the future; expectations regarding additional public and private reimbursement coverage for our tests worldwide and the ability of additional coverage to result in additional revenue; and the company's methodology for calculating financial performance under the new ASC 606 accounting standard as compared against prior periods under the previously applicable ASC 605 accounting standard. Forward-looking statements are subject to risks and uncertainties that could cause actual results to differ materially, and reported results should not be considered as an indication of future performance. These risks and uncertainties include, but are not limited to: the risk that the company may not achieve expected revenue growth for the remainder of 2018; the risks and uncertainties associated with the regulation of the company's tests; the results of clinical studies and their impact on reimbursement and adoption; the applicability of clinical study results to actual outcomes; the company's ability to develop and commercialize new tests and expand into new markets domestically and internationally; the commercial success of any collaborations entered into by the company; the risk that the company may not obtain or maintain sufficient levels of reimbursement, domestically or abroad, for its existing tests and any future tests it may develop; the risks of competition; unanticipated costs or delays in research and development efforts; the company's ability to obtain capital when needed and the other risks set forth in the company's filings with the Securities and Exchange Commission, including the risks set forth in the company's Quarterly Report on Form 10-Q for the quarter ended June 30, 2018. These forward-looking statements speak only as of the date hereof. Genomic Health disclaims any obligation to update these forward-looking statements.

NOTE: The Genomic Health logo, Oncotype, Oncotype DX, Breast Recurrence Score, DCIS Score, Oncotype SEQ, Liquid Select, Genomic Prostate Score, GPS, Oncotype DX AR-V7 Nucleus Detect, and Oncotype IQ are trademarks or registered trademarks of Genomic Health, Inc. All other trademarks and service marks are the property of their respective owners.


                                                            
            
                GENOMIC HEALTH, INC.


                                                    
        
              Condensed Consolidated Statements of Operations


                                                      
          
              (In thousands, except per share amounts)


                                                               
             
                (Unaudited)






                                   Three Months Ended                                              Nine Months Ended


                                      September 30,                                                September 30,



                                                 2018                            2017                                  2018 2017




     REVENUES:


      Product revenues -United
       States                                           $
            85,747                                $
              70,881            246,054  $
      213,878


      Product revenues -Outside
       of the United States                                       15,511                                            12,940             43,448       39,409




     Total revenues                                             101,258                                            83,821            289,502      253,287




      OPERATING EXPENSES (1)(2):


      Cost of product revenues                                    15,518                                            13,433             48,635       40,904


      Research and development                                    15,433                                            17,212             47,552       47,868


      Selling and marketing                                       40,051                                            38,303            122,143      120,464


      General and administrative                                  18,498                                            17,505             56,702       52,651



      Total operating expenses                                    89,500                                            86,453            275,032      261,887





      Income (loss) from
       operations                                                 11,758                                           (2,632)            14,470      (8,600)





     Interest income                                                676                                               263              1,492          627


      Unrealized gain on
       investments, net                                              127                                                               1,538


      Gain on sales of marketable
       securities                                                                                                                                 2,807


      Other income (expense), net                                     39                                               340                101          792



      Income (loss) before income
       taxes                                                      12,600                                           (2,029)            17,601      (4,374)


      Income tax expense                                             375                                               162                834        1,362




     Net income (loss)                                 $
            12,225                               $
              (2,191)       $
       16,767  $
      (5,736)



      Basic net income (loss) per
       share                                              $
            0.34                                $
              (0.06)         $
       0.47   $
      (0.17)



      Diluted net income (loss)
       per share                                          $
            0.32                                $
              (0.06)         $
       0.45   $
      (0.17)



      Shares used in computing
       basic net income (loss) per
       share                                                      35,925                                            34,675             35,558       34,373



      Shares used in computing
       diluted net income (loss)
       per share.                                                 38,026                                            34,675             37,044       34,373






              (1)              Included in
                                  operating
                                  expenses for the
                                  three months
                                  ended September
                                  30, 2018 were
                                  non-cash charges
                                  of $8.5 million,
                                  including $5.4
                                  million of stock-
                                  based
                                  compensation
                                  expense and $3.1
                                  million of
                                  depreciation and
                                  amortization
                                  expenses,
                                  compared with
                                  non-cash charges
                                  for the same
                                  period in 2017 of
                                  $8.1 million,
                                  including $5.0
                                  million of stock-
                                  based
                                  compensation
                                  expense and $3.1
                                  million of
                                  depreciation and
                                  amortization
                                  expenses.





              (2)              Included in
                                  operating
                                  expenses for the
                                  nine months ended
                                  September 30,
                                  2018 were non-
                                  cash charges of
                                  $25.1 million,
                                  including $15.7
                                  million of stock-
                                  based
                                  compensation
                                  expense and $9.4
                                  million of
                                  depreciation and
                                  amortization
                                  expenses,
                                  compared with
                                  non-cash charges
                                  for the same
                                  period in 2017 of
                                  $23.8 million,
                                  including $15.2
                                  million of stock-
                                  based
                                  compensation
                                  expense and $8.6
                                  million of
                                  depreciation and
                                  amortization
                                  expenses.


                                       
              
               GENOMIC HEALTH, INC.


                                  
           
               Condensed Consolidated Balance Sheets


                                          
             
                (In thousands)






                                        As of                                                 As of


                                    September 30,                                         December 31,


                                             2018                                                  2017



                                     (Unaudited)                                                   (1)




      Cash and cash equivalents                           $
              69,242                             $
         45,518


      Short-term marketable
       securities (2)                                                114,021                                    84,057


      Accounts receivable, net                                        51,553                                    31,161


      Prepaid expenses and other
       current assets                                                 11,886                                    13,524



      Total current assets                                           246,702                                   174,260




      Property and equipment, net                                     39,804                                    46,440



     Other assets                                                    13,860                                    10,917




     Total assets                                       $
              300,366                            $
         231,617






     Accounts payable                                     $
              6,545                                $
         156


      Accrued expenses and other
       current liabilities                                            43,860                                    39,360


      Other liabilities                                                3,944                                     3,810


      Stockholders' equity                                           246,017                                   188,291



      Total liabilities and
       stockholders' equity                              $
              300,366                            $
         231,617






              (1)              The condensed
                                  consolidated
                                  balance sheet at
                                  December 31,
                                  2017, has been
                                  derived from the
                                  audited
                                  consolidated
                                  financial
                                  statements at
                                  that date
                                  included in the
                                  company's Annual
                                  Report on Form
                                  10-K for the
                                  fiscal year ended
                                  December 31,
                                  2017.





              (2)              Included in short-
                                  term marketable
                                  securities as of
                                  September 30,
                                  2018 and December
                                  31, 2017 is $3.8
                                  million and $3.5
                                  million,
                                  respectively, of
                                  corporate equity
                                  securities,
                                  representing the
                                  company's
                                  investment in
                                  Biocartis N.V.


                                                                      
         
                GENOMIC HEALTH, INC.


                                                                   
          
            GAAP to Non-GAAP Reconciliations


                                                                        
          
                (In thousands)


                                                                         
          
                (Unaudited)






                                                Three Months Ended                                           Nine Months Ended


                                                   September 30,                                             September 30,



                                                              2018                         2017                                  2018 2017



                  Income (loss) from operations
                   reconciliation:


     GAAP income (loss) from
      operations                                                     $
         11,758                               $
              (2,632)       $
        14,470  $
        (8,600)


     Cost of product revenues -
      cessation of Oncotype SEQ                                                                                                                  3,519


     Research and development -
      cessation of Oncotype SEQ                                                                                                                  3,039


     Selling and marketing -
      cessation of Oncotype SEQ                                                                                                                  1,064


     General and administrative -
      cessation of Oncotype SEQ                                                                                                                    909


     Research and development -
      Biocartis license and option
      fee                                                                    1,169                                             3,249               1,169          3,249


     Research and development -
      milestone payment Biocartis                                                                                                                  990


     Research and development -
      Cleveland Diagnostics
      cancellation of collaboration
      agreement                                                                                                                                  1,329



     Non-GAAP income (loss) from
      operations                                                     $
         12,927                                   $
              617        $
        26,489  $
        (5,351)





                  Net income (loss)
                   reconciliation:


     GAAP net income (loss)                                          $
         12,225                               $
              (2,191)       $
        16,767  $
        (5,736)


     Cost of product revenues -
      cessation of Oncotype SEQ                                                                                                                  3,519


     Research and development -
      cessation of Oncotype SEQ                                                                                                                  3,039


     Selling and marketing -
      cessation of Oncotype SEQ                                                                                                                  1,064


     General and administrative -
      cessation of Oncotype SEQ                                                                                                                    909


     Research and development -
      Biocartis license and option
      fee                                                                    1,169                                             3,249               1,169          3,249


     Research and development -
      milestone payment Biocartis                                                                                                                  990


     Research and development -
      Cleveland Diagnostics
      cancellation of collaboration
      agreement                                                                                                                                  1,329


     Other income - Biocartis -
      change in fair value                                                    (56)                                                               (295)


     Other income - Epic Sciences -
      revaluation of investment                                                                                                                (1,171)


     Non-recurring gain on sale of
      marketable securities                                                                                                                                  (2,807)


     Reduced income tax expense from
      the sale of marketable
      securities                                                                                                                                                 821



     Non-GAAP net income (loss)                                      $
         13,338                                 $
              1,058        $
        27,320  $
        (4,473)


                                                                               
             
                GENOMIC HEALTH, INC.


                                                                         
         
               Non-GAAP Constant Currency Reconciliations


                                                                                 
              
                (In thousands)


                                                                                   
              
                (Unaudited)






                                                      Three Months Ended                                               Nine Months Ended


                                                         September 30,                                                 September 30,



                                                                    2018                               2017                                 2018 2017



                   Constant currency reconciliations:


                   International Revenue:



     International revenue (1)                                             $
            15,511                                       $
        12,682        $
        43,448  $
      38,621


         Currency exchange adjustments (2)                                             (305)                                                              (1,393)



      Non-GAAP International revenue                                        $
            15,206                                       $
        12,682        $
        42,055  $
      38,621



         Period over period constant currency
          increase                                                                     2,524                                                                 3,434


         Period over period constant currency
          increase percentage                                                            20%                                                                   9%




                   Total Revenue:



     Total revenue (1)                                                    $
            101,258                                       $
        82,150       $
        289,502 $
      248,237


         Currency exchange adjustments (2)                                             (305)                                                              (1,393)




     Non-GAAP total revenue                                               $
            100,953                                       $
        82,150       $
        288,109 $
      248,237



         Period over period constant currency
          increase                                                                    18,803                                                                39,872


         Period over period constant currency
          increase percentage                                                            23%                                                                  16%






              (1)              For the three and
                                  nine months ended
                                  September 30,
                                  2018,
                                  International
                                  revenue and total
                                  revenue is based
                                  on GAAP under ASC
                                  606 and for the
                                  three and nine
                                  months ended
                                  September 30,
                                  2017,
                                  International
                                  revenue and total
                                  revenue is based
                                  on the Pre-606
                                  Adjusted revenue
                                  on the following
                                  table.





              (2)              Constant currency
                                  is a non-GAAP
                                  measure that is
                                  calculated by
                                  comparing the
                                  company's
                                  quarterly average
                                  foreign exchange
                                  rates for the
                                  three and nine
                                  months ended
                                  September 30,
                                  2018 and 2017.
                                  The constant
                                  currency
                                  disclosures take
                                  current local
                                  currency revenue
                                  and translate it
                                  into U.S. dollars
                                  based upon the
                                  foreign currency
                                  exchange rates
                                  used to translate
                                  the local
                                  currency revenue
                                  for the
                                  applicable
                                  comparable period
                                  in the prior
                                  year, rather than
                                  the actual
                                  exchange rates in
                                  effect during the
                                  current period.
                                  It does not
                                  include any other
                                  effect of changes
                                  in foreign
                                  currency rates on
                                  the company's
                                  results or
                                  business.


                                                            
           
                GENOMIC HEALTH, INC.


                                              
              
             Non-GAAP Supplemental Financial Information (1)


                                                               
           
                (In thousands)


                                                                
           
                (Unaudited)




                                                Three Months Ended                                                 Nine Months Ended


                                                   September 30,                                                     September 30,


                                                              2017                                                               2017



                  U.S. Product revenue, under
                   ASC 605:


     Invasive breast test
      revenue                                                                       $
              63,050                                $
      193,516


     Prostate test revenue                                                                       5,501                                     12,940


     All other test revenue                                                                      2,330                                      7,422



     Total U.S. product revenue                                                                 70,881                                    213,878



                  Adjustment related to new
                   ASC 606 accounting
                   standard:


     Invasive breast test
      revenue                                                                                    1,413                                      4,251


     Prostate test revenue


     All other test revenue



     Total ASC 606 adjustment to
      U.S. product revenue                                                                       1,413                                      4,251



                  Pre-606 Adjusted U.S.
                   Product revenue, net of
                   adjustments:


     Invasive breast test
      revenue                                                                                   61,637                                    189,266


     Prostate test revenue                                                                       5,501                                     12,940


     All other test revenue                                                                      2,330                                      7,421



     Total Pre-606 Adjusted
      U.S. product revenue                                                          $
              69,468                                $
      209,627





                  International product
                   revenue, under ASC 605:


     Invasive breast test
      revenue                                                                       $
              12,811                                 $
      38,919


     Prostate test revenue                                                                          41                                        106


     All other test revenue                                                                         88                                        384



     Total International product
      revenue                                                                                   12,940                                     39,409



                  Adjustment related to new
                   ASC 606 accounting
                   standard:


     Invasive breast test
      revenue                                                                                      258                                        799


     Prostate test revenue


     All other test revenue



     Total ASC 606 adjustment to
      International product
      revenue                                                                                      258                                        799



                  Pre-606 Adjusted
                   International product
                   revenue, net of
                   adjustments:


     Invasive breast test
      revenue                                                                                   12,553                                     38,120


     Prostate test revenue                                                                          41                                        106


     All other test revenue                                                                         88                                        384



     Total Pre-606 Adjusted
      International product
      revenue                                                                       $
              12,682                                 $
      38,610





                  Total Product Revenue,
                   under ASC 605:


     Invasive breast test
      revenue                                                                       $
              75,861                                $
      232,435


     Prostate test revenue                                                                       5,542                                     13,046


     All other test revenue                                                                      2,418                                      7,806



     Total product revenue                                                                      83,821                                    253,287



                  Adjustment related to new
                   ASC 606 accounting
                   standard:


     Invasive breast test
      revenue                                                                                    1,671                                      5,050


     Prostate test revenue


     All other test revenue



     Total ASC 606 adjustment to
      total product revenue                                                                      1,671                                      5,050



                  Pre-606 Adjusted Total
                   product revenue, net of
                   adjustments:


     Invasive breast test
      revenue                                                                                   74,190                                    227,386


     Prostate test revenue                                                                       5,542                                     13,046


     All other test revenue                                                                      2,418                                      7,806



     Total Pre-606 Adjusted
      total product revenue                                                         $
              82,150                                $
      248,237


            
              
                GENOMIC HEALTH, INC.


                            Non-GAAP Supplemental Financial Information
                                             (1)


               
              
                (In thousands)


                
              
                (Unaudited)





              (1)              Effective January 1, 2018, the
                                  company adopted new accounting
                                  guidance ASC Topic 606 ("ASC
                                  606"), related to revenue from
                                  contracts with customers, using
                                  a modified retrospective method.
                                  Since the 2017 annual and
                                  quarterly financial statements
                                  will not be restated to reflect
                                  ASC 606, the company is
                                  providing this supplemental
                                  schedule to present 2017 revenue
                                  reflecting an estimate as if ASC
                                  606 had been applied effective
                                  January 1, 2017. This Pre-606
                                  adjusted revenue information is
                                  intended to provide investors
                                  with a basis for considering the
                                  potential directional impact the
                                  adoption of ASC 606 might have
                                  on the company's financial
                                  information that will be
                                  reported in 2018. The Pre-606
                                  adjusted revenue information is
                                  provided only for illustrative
                                  purposes and does not constitute
                                  a restatement of the company's
                                  historical financial statements
                                  previously filed with the SEC,
                                  which should be considered by
                                  investors in their entirety as
                                  filed.

GHDX-F

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SOURCE Genomic Health, Inc.