Penumbra, Inc. Reports Fourth Quarter and Full Year 2024 Financial Results

ALAMEDA, Calif., Feb. 18, 2025 /PRNewswire/ -- Penumbra, Inc. (NYSE: PEN), the world's leading thrombectomy company, today reported financial results for the fourth quarter and full year ended December 31, 2024.

Financial Highlights:

    --  Adjusted revenue(1) of $321.3 million, excluding the $5.8 million impact
        of the Italian government's payback provision pertaining to prior years,
        an increase of 12.9% adjusted(2) or 13.0% in adjusted constant
        currency(2) compared to the fourth quarter of 2023.
    --  Adjusted revenue(1 )of $1,200.4 million, excluding the $5.8 million
        impact of the Italian government's payback provision pertaining to prior
        years, an increase of 13.4% in adjusted(2) and adjusted constant
        currency(2) compared to the full year 2023.
    --  Revenue of $315.5 million for the fourth quarter of 2024, an increase of
        10.8% in reported and constant currency(2) compared to the fourth
        quarter of 2023.
    --  Revenue of $1,194.6 million for the full year 2024, an increase of 12.9%
        or 12.8% in constant currency(2 )compared to the full year 2023.
    --  Income from operations of $42.8 million and Non-GAAP income from
        operations(2) of $48.6 million in the fourth quarter of 2024.
    --  Income from operations of $9.3 million and Non-GAAP income from
        operations(2) of $106.6 million for the full year 2024.
    --  Net income of $33.7 million and adjusted EBITDA(2) of $63.7 million or
        net income margin of 10.7% and adjusted EBITDA margin(2) of 19.8% in the
        fourth quarter of 2024.
    --  Net income of $14.0 million and adjusted EBITDA(2) of $171.0 million or
        net income margin of 1.2% and adjusted EBITDA margin(2) of 14.2% for the
        full year 2024.

Fourth Quarter 2024 Financial Results
Adjusted total revenue(1 )increased to $321.3 million for the fourth quarter of 2024 compared to $284.7 million for the fourth quarter of 2023, an increase of 12.9% adjusted(2) or 13.0% in adjusted constant currency(2). The United States represented 77.2% of adjusted total revenue(1) and international represented 22.8% of adjusted total revenue(1) for the fourth quarter of 2024. Adjusted total revenue(1) from the U.S. increased 21.7% while revenue from our international regions decreased 9.4% adjusted(2), or 9.1% in adjusted constant currency(2). Adjusted total revenue(1 )from sales of our global thrombectomy products grew to $222.7 million in the fourth quarter of 2024, an increase of 16.8% adjusted(2), or 16.9% in adjusted constant currency(2) over the same period a year ago, driven primarily by the sales our U.S. thrombectomy products which increased by 27.3% which was partially offset by a 13.9% decline in adjusted revenue(1) from international regions due to a decline in China revenue offset in part by increases in all other international regions. Adjusted total revenue(1) from sales of our global embolization and access products grew to $98.6 million in the fourth quarter of 2024, an increase of 5.0% adjusted(2), or 5.1% in adjusted constant currency(2) over the same period a year ago, driven primarily by our U.S embolization and access products.

Total revenue increased to $315.5 million for the fourth quarter of 2024 compared to $284.7 million for the fourth quarter of 2023, an increase of 10.8% in reported and constant currency(2). The United States represented 78.6% of total revenue and international represented 21.4% of total revenue for the fourth quarter of 2024. Revenue from the U.S. increased 21.7% while revenue from our international regions decreased 16.5%, or 16.6% in constant currency(2). Revenue from sales of our global thrombectomy products grew to $220.1 million in the fourth quarter of 2024, an increase of 15.4% in reported and constant currency(2) over the same period a year ago, driven primarily by the sales of our U.S. thrombectomy products which increased by 27.3%. Revenue from sales of our global embolization and access products grew to $95.4 million in the fourth quarter of 2024, an increase of 1.6%, or 1.5% in constant currency(2) from the same period a year ago, driven primarily by our U.S. embolization and access products which increased by 8.9% from the same period a year ago.

Gross profit, including the $5.8 million impact of the Italian government's payback provision pertaining to prior years, for the fourth quarter of 2024 was $210.7 million, or 66.8% of total revenue. Excluding the impact of the Italian government's payback provision, adjusted gross profit(2) was $216.5 million, or 67.4% of adjusted total revenue(1 )for the fourth quarter of 2024 compared to GAAP and adjusted gross profit(2) of $187.0 million, or 65.7% of total revenue for the fourth quarter of 2023. Gross margin is impacted by product mix, regional mix, and production initiatives to support demand and create future efficiencies. As such, with favorable product mix, improvement in productivity, and by leveraging our fixed costs on higher volume of new product sales during the year, our gross margin may be positively impacted in the future.

Total operating expenses and total non-GAAP operating expenses(2) were $167.9 million, or 53.2% of total revenue and 52.3% of adjusted revenue(1 )for the fourth quarter of 2024. This compares to total operating expenses of $152.0 million, or 53.4% of total revenue for the fourth quarter of 2023, which included a $2.4 million amortization expense of finite lived intangible assets acquired in connection with the Sixense acquisition. Excluding the charge noted above, total non-GAAP operating expenses(2 )were $149.6 million, or 52.5% of total revenue for the fourth quarter of 2023. R&D expenses were $20.0 million for the fourth quarter of 2024, compared to $21.9 million for the fourth quarter of 2023. SG&A expenses were $147.9 million for the fourth quarter of 2024, compared to $130.0 million for the fourth quarter of 2023.

Income from operations was $42.8 million for the fourth quarter of 2024 compared to income from operations of $35.0 million for the fourth quarter of 2023. Excluding the $5.8 million impact of the Italian government's payback provision pertaining to prior years, non-GAAP income from operations(2) was $48.6 million for the fourth quarter of 2024. This compares to non-GAAP income from operations(2) of $37.4 million for the fourth quarter of 2023, which excludes the amortization expense of finite lived intangible assets acquired in connection with the Sixense acquisition.

Full Year 2024 Financial Results
Adjusted total revenue(1 )increased to $1,200.4 million for the year ended December 31, 2024, an increase of 13.4% in adjusted(2) and adjusted constant currency(2) compared to $1,058.5 million for the year ended December 31, 2023.

Total revenue increased to $1,194.6 million for the year ended December 31, 2024 compared to $1,058.5 million for the year ended December 31, 2023, an increase of 12.9%, or 12.8% in constant currency(2). The United States represented 75.5% of total revenue and international represented 24.5% of total revenue for the year ended December 31, 2024. Revenue from the U.S. increased 19.1% while revenue from our international regions decreased 2.9%, or 3.1% in constant currency(2). Revenue from sales of our global thrombectomy products grew to $815.5 million for the year ended December 31, 2024, an increase of 20.4% in reported and constant currency(2) over the same period a year ago, driven primarily by the sales of our U.S. thrombectomy products which increased by 26.8%. Revenue from sales of our global embolization and access products declined to $379.1 million for the year ended December 31, 2024, a decrease of 0.5%, or 0.7% in constant currency(2) from the same period a year ago, driven primarily by our international embolization and access products which decreased by 7.6%, or 7.9% in constant currency(2), partially offset by a 3.3% increase in sales of our U.S. embolization and access products.

Gross profit, including the $5.8 million impact of the Italian government's payback provision pertaining to prior years and a one-time $33.4 million inventory impairment charge to cost of revenue in connection with the impairment of our Immersive Healthcare asset group, for the year ended December 31, 2024 was $755.0 million, or 63.2% of total revenue, compared to $682.6 million, or 64.5% of total revenue, for the year ended December 31, 2023. The impact of the $5.8 million Italian payback provision and one-time $33.4 million charge decreased our gross margin by 3.0 percentage points in 2024. Gross margin is impacted by product mix, regional mix, and production initiatives to support demand and create future efficiencies. As such, with favorable product mix, improvement in productivity, and by leveraging our fixed costs on higher volume of new product sales during the year, our gross margin may be positively impacted in the future.

Total operating expenses for the year ended December 31, 2024 were $745.7 million, or 62.4% of total revenue, which included $5.0 million of one-time expenses in connection with the wind down of the Immersive Healthcare business, a $76.9 million long-lived asset impairment charge associated with the impairment of assets related to our Immersive Healthcare business, $4.8 million in non-recurring litigation related expenses, and a $4.8 million amortization expense of finite lived intangible assets acquired in connection with the Sixense acquisition. This compares to total operating expenses of $609.1 million, or 57.5% of total revenue, for the year ended December 31, 2023, which included a one-time $18.2 million expense associated with the acquisition of in-process research and development ("IPR&D") and a $9.5 million amortization expense of finite lived intangible assets acquired in connection with the Sixense acquisition. Excluding the charges noted above, total non-GAAP operating expenses(2 )were $654.2 million, or 54.8% of total revenue during the year ended December 31, 2024, and $581.4 million, or 54.9% of total revenue during the year ended December 31, 2023. R&D expenses were $94.8 million for the year ended December 31, 2024, compared to $84.4 million for the year ended December 31, 2023. SG&A expenses were $574.0 million for the year ended December 31, 2024, compared to $506.5 million for the year ended December 31, 2023.

Income from operations was $9.3 million for the year ended December 31, 2024 compared to income from operations of $73.6 million for the year ended December 31, 2023. Excluding impact of the Italian government's payback provision of $5.8 million, one-time expenses in connection with the wind down of the Immersive Healthcare business of $5.0 million, a $76.9 million long-lived asset impairment charge associated with the impairment of assets related to our Immersive Healthcare business, $4.8 million in non-recurring litigation related expenses, and amortization expense of finite lived intangible assets acquired in connection with the Sixense acquisition of $4.8 million, non-GAAP income from operations(2) was $106.6 million for the year ended December 31, 2024. This compares to non-GAAP income from operations(2) of $101.3 million for the year ended December 31, 2023, excluding the one-time expense associated with the acquired IPR&D of $18.2 million and the amortization expense of finite lived intangible assets acquired in connection with the Sixense acquisition of $9.5 million.



     
     (1)Adjusted revenue excludes $5.8 million due to the Italian government's payback provision.



     
     (2)See "Non-GAAP Financial Measures" for important information about our use of non-GAAP measures.

Full Year 2025 Financial Outlook
The Company projects total revenue for 2025 to be in the range of $1,340.0 million to $1,360.0 million, representing year over year growth of 12% to 14% compared to 2024 revenue of $1,194.6 million. The Company projects the U.S. thrombectomy franchise will grow 19% to 20% year-over-year, driven primarily by its computer assisted vacuum thrombectomy (CAVT) products. The Company expects gross margin expansion of at least 100 basis points in 2025, to more than 67% for the full year, and operating margin expansion to a range of 13% to 14% of revenue for full year 2025.

Webcast and Conference Call Information
Penumbra, Inc. will host a conference call to discuss financial results for the fourth quarter and year ended December 31, 2024 after market close on Tuesday, February 18, 2025 at 4:30 PM Eastern Time. The conference call can be accessed live over the phone by dialing (888) 596-4144 (conference id: 5872954), or the webcast can be accessed on the "Events and Presentations" section under the "Investors" tab of the Company's website at: www.penumbrainc.com. The webcast will be available on the Company's website for at least two weeks following the completion of the call.

About Penumbra
Penumbra, Inc., the world's leading thrombectomy company, is focused on developing the most innovative technologies for challenging medical conditions such as ischemic stroke, venous thromboembolism such as pulmonary embolism, and acute limb ischemia. Our broad portfolio, which includes computer assisted vacuum thrombectomy (CAVT), centers on removing blood clots from head-to-toe with speed, safety and simplicity. By pioneering these innovations, we support healthcare providers, hospitals and clinics in more than 100 countries, working to improve patient outcomes and quality of life. For more information, visit www.penumbrainc.com and connect on Instagram, LinkedIn, and X.

Non-GAAP Financial Measures
In addition to financial measures prepared in accordance with U.S. generally accepted accounting principles ("GAAP"), the Company uses the following non-GAAP financial measures in this press release: a) constant currency and adjusted constant currency, b) adjusted revenue, adjusted gross profit, adjusted gross margin, non-GAAP operating expenses, non-GAAP income from operations, non-GAAP net income and non-GAAP diluted earnings per share ("EPS") and c) adjusted EBITDA.

Constant currency and adjusted constant currency. The Company's constant currency revenue disclosures estimate the impact of changes in foreign currency rates on the translation of the Company's current period revenue as compared to the applicable comparable period in the prior year. This impact is derived by taking the current local currency revenue and translating it into U.S. dollars based upon the foreign currency exchange rates used to translate the local currency revenue for the applicable comparable period in the prior year, rather than the actual exchange rates in effect during the current period. It does not include any other effect of changes in foreign currency rates on the Company's results or business. The Company's adjusted constant currency revenue disclosures are calculated in the same manner as above but uses adjusted revenue, described below, and accordingly excludes the impact of the Italian government's payback provision pertaining to prior years.

Adjusted Revenue. The adjustments to the GAAP financial measure reflect the exclusion of impact of the Italian government's payback provision pertaining to prior years. During the year ended December 31, 2024, the Company recorded a reduction in revenue of $7.3 million related to the Italian payback provision pertaining to the years 2015 through 2024, of which $5.8 million pertained to prior years.

Adjusted gross profit and adjusted gross margin. The adjustments to the GAAP financial measures reflect the exclusion of impact of the Italian government's payback provision pertaining to prior years.

Non-GAAP operating expenses, non-GAAP income from operations, non-GAAP net income and non-GAAP diluted EPS. The adjustments to the GAAP financial measures reflect the exclusion of:

    --  the one-time expense associated with the acquisition of IPR&D in the
        third quarter of 2023;
    --  the effect of the amortization of finite lived intangible assets
        acquired in connection with the Sixense acquisition over their estimated
        useful lives;
    --  the excess tax benefits associated with share-based compensation
        arrangements;
    --  the release of the valuation allowance associated with Federal R&D tax
        credits and partial release of the valuation allowance associated with
        California deferred tax assets;
    --  non-recurring litigation related expenses;
    --  non-cash long-lived asset impairment related to the impairment of our
        Immersive Healthcare asset group;
    --  one-time expenses in connection with the wind down of the Immersive
        Healthcare business; and
    --  the Italian government's payback provision pertaining to prior years.

Adjusted EBITDA. The Company's adjusted EBITDA reflects the exclusion from GAAP net income of:

    --  non-cash operating charges such as stock-based compensation,
        depreciation and amortization, and impairment charges;
    --  non-operating items such as the one-time expense associated with the
        acquisition of IPR&D, interest income, interest expense, and provision
        for (benefit from) income taxes;
    --  non-recurring litigation related expenses;
    --  one-time expenses in connection with the wind down of the Immersive
        Healthcare business; and
    --  the Italian government's payback provision pertaining to prior years.

Full reconciliation of these non-GAAP measures to the most comparable GAAP measures is set forth in the tables below.

Our management believes the non-GAAP financial measures disclosed in this press release are useful to investors in assessing the operating performance of our business and provide meaningful comparisons to prior periods and thus a more complete understanding of our business than could be obtained absent this disclosure. Specifically, we consider the change in constant currency revenue as a useful metric as it provides an alternative framework for assessing how our underlying business performed excluding the effect of foreign currency rate fluctuations. We consider adjusted revenue, adjusted gross profit and adjusted gross margin useful metrics to investors as they eliminate the impact of the Italian government's payback provision pertaining to prior years and allow a more direct comparison of our business performance between periods. We consider non-GAAP operating expenses, non-GAAP income from operations, non-GAAP net income and non-GAAP diluted EPS useful metrics as they provide an alternative framework for assessing how our underlying business performed excluding the one-time expense associated with the acquisition of IPR&D in the third quarter of 2023, the amortization expense of finite lived intangible assets acquired in connection with the Sixense acquisition, the excess tax benefits associated with share-based compensation arrangements, the release of the valuation allowance associated with Federal R&D tax credits and partial release of the valuation allowance associated with California deferred tax assets, expenses related to certain litigation matters that we have determined are not a normal or recurring part of our business, including settlement costs and legal fees, non-cash long-lived asset impairment related to the impairment of our Immersive Healthcare asset group, one-time expenses in connection with the wind down of the Immersive Healthcare business, and the Italian government's payback provision pertaining to prior years. Further, we consider adjusted EBITDA a useful metric as it provides an alternative framework for assessing how our underlying business performed excluding the Italian government's payback provision pertaining to prior years, non-cash operating charges such as stock-based compensation, depreciation and amortization, and impairment charges, non-operating items such as the one-time expense associated with the acquisition of IPR&D, interest income, interest expense, and provision for (benefit from) income taxes, non-recurring litigation related expenses, and one-time expenses in connection with the wind down of the Immersive Healthcare business.

The non-GAAP financial measures included in this press release may be different from, and therefore may not be comparable to, similarly titled measures used by other companies. These non-GAAP measures should not be considered in isolation or as alternatives to GAAP measures. We urge investors to review the reconciliation of these non-GAAP financial measures to the comparable GAAP financial measures included in this press release, and not to rely on any single financial measure to evaluate our business.

Forward-Looking Statements
Except for historical information, certain statements in this press release are forward-looking in nature and are subject to risks, uncertainties and assumptions about us. Our business and operations are subject to a variety of risks and uncertainties and, consequently, actual results may differ materially from those projected by any forward-looking statements. Factors that could cause actual results to differ from those projected include, but are not limited to: failure to sustain or grow profitability or generate positive cash flows; failure to effectively introduce and market new products; delays in product introductions; significant competition; inability to further penetrate our current customer base, expand our user base and increase the frequency of use of our products by our customers; inability to achieve or maintain satisfactory pricing and margins; manufacturing difficulties; permanent write-downs or write-offs of our inventory or other assets; product defects or failures; unfavorable outcomes in clinical trials; inability to maintain our culture as we grow; fluctuations in foreign currency exchange rates; potential adverse regulatory actions; and the potential impact of any acquisitions, mergers, dispositions, joint ventures or investments we may make. These risks and uncertainties, as well as others, are discussed in greater detail in our filings with the Securities and Exchange Commission ("SEC"), including our Annual Report on Form 10-K for the year ended December 31, 2024, which we expect to file with the SEC on or before March 3, 2025. There may be additional risks of which we are not presently aware or that we currently believe are immaterial which could have an adverse impact on our business. Any forward-looking statements are based on our current expectations, estimates and assumptions regarding future events and are applicable only as of the dates of such statements. We make no commitment to revise or update any forward-looking statements in order to reflect events or circumstances that may change.


                                  
              
                Penumbra, Inc.


                       
              
                Condensed Consolidated Balance Sheets


                                    
              
                (unaudited)


                                  
              
                (in thousands)




                                                                                                December 31,


                                                                                           2024         2023



     
                Assets



     Current assets:



          Cash and cash equivalents                                                   $324,404     $167,486



          Marketable investments                                                        15,727      121,701



          Accounts receivable, net                                                     167,668      201,768



          Inventories                                                                  406,737      388,023



          Prepaid expenses and other current assets                                     36,589       36,424



               Total current assets                                                    951,125      915,402



     Property and equipment, net                                                        62,641       72,691



     Operating lease right-of-use assets                                               177,787      188,756



     Finance lease right-of-use assets                                                  28,018       31,092



     Intangible assets, net                                                              6,513       71,056



     Goodwill                                                                          165,826      166,270



     Deferred taxes                                                                    100,332       85,158



     Other non-current assets                                                           40,939       25,880



               Total assets                                                         $1,533,181   $1,556,305



     
                Liabilities and Stockholders' Equity



     Current liabilities:



          Accounts payable                                                             $31,326      $27,155



          Accrued liabilities                                                          112,429      110,555



          Current operating lease liabilities                                           12,221       11,203



          Current finance lease liabilities                                              2,369        2,231



               Total current liabilities                                               158,345      151,144



     Non-current operating lease liabilities                                           187,068      197,229



     Non-current finance lease liabilities                                              21,731       23,680



     Other non-current liabilities                                                      15,106        5,308



               Total liabilities                                                       382,250      377,361



     Stockholders' equity:



     Preferred stock



     Common stock                                                                           38           39



     Additional paid-in capital                                                      1,096,732    1,047,198



     Accumulated other comprehensive loss                                              (5,843)     (3,151)



     Retained earnings                                                                  60,004      134,858



     Total stockholders' equity                                                      1,150,931    1,178,944



     Total liabilities and stockholders' equity                                     $1,533,181   $1,556,305


                                                        
           
                Penumbra, Inc.


                                          
              
          Condensed Consolidated Statements of Operations


                                                         
           
                (unaudited)


                                         
              
          (in thousands, except share and per share amounts)




                                                                                                                Three Months Ended December 31,                  Year Ended December 31,


                                                                                                           2024           2023                   2024       2023



     Revenue                                                                                          $315,518       $284,679             $1,194,615 $1,058,522



     Cost of revenue                                                                                   104,797         97,687                439,620    375,879



          Gross profit                                                                                 210,721        186,992                754,995    682,643



     Operating expenses:



          Research and development                                                                      20,010         21,942                 94,783     84,423



          Sales, general and administrative                                                            147,936        130,021                573,988    506,454



          Acquired in-process research and development                                                                                                18,215



          Impairment Charge                                                                                                                 76,945



               Total operating expenses                                                                167,946        151,963                745,716    609,092



     Income from operations                                                                             42,775         35,029                  9,279     73,551



     Interest and other income (expense), net                                                            1,564          3,129                 11,590      6,099



     Income before income taxes                                                                         44,339         38,158                 20,869     79,650



     Provision for (benefit from) income taxes                                                          10,656       (16,060)                 6,857   (11,304)



     Net income                                                                                        $33,683        $54,218                $14,012    $90,954





     Net income per share:



     Basic                                                                                               $0.88          $1.40                  $0.36      $2.37



     Diluted                                                                                             $0.86          $1.38                  $0.36      $2.32



     Weighted average shares outstanding:



     Basic                                                                                          38,418,269     38,628,565             38,633,744 38,401,171



     Diluted                                                                                        39,037,644     39,291,044             39,268,037 39,216,564


                                                                    
              
                Penumbra, Inc.


                  
              
                Reconciliation of GAAP Revenue, GAAP Gross Profit and GAAP Gross Margin to Adjusted Revenue, Non-GAAP Gross Profit
                                                                         and Non-GAAP Gross Margin(1)


                                                                     
              
                (unaudited)


                                                    
              
                (in thousands, except for percentages)




                                                                                                                                              Three Months Ended December 31,                   Year Ended December 31,


                                                                                                                                 2024                    2023                   2024       2023



     GAAP revenue                                                                                                           $315,518                $284,679             $1,194,615 $1,058,522



     Italian payback measure(2)                                                                                                5,797                                         5,797



     Adjusted revenue(2)                                                                                                     321,315                 284,679              1,200,412  1,058,522





     GAAP gross profit                                                                                                       210,721                 186,992                754,995    682,643



     GAAP gross profit includes the effect of the following item:



     Italian payback measure(2)                                                                                                5,797                                         5,797



     Adjusted gross profit                                                                                                  $216,518                $186,992               $760,792   $682,643



     GAAP gross margin                                                                                                        66.8 %                 65.7 %                63.2 %    64.5 %



     Adjusted gross margin                                                                                                    67.4 %                 65.7 %                63.4 %    64.5 %




     
     (1)See "Non-GAAP Financial Measures" for important information about our use of non-GAAP measures.



     
     (2)Represents the impact of the Italian government's payback provision pertaining to prior years during the three months ended December 31, 2024.


                                                                               
              
                Penumbra, Inc.


                                
              
                Reconciliation of GAAP Operating Expenses and GAAP Income from Operations to Non-GAAP Operating Expenses and
                                                                                 Non-GAAP Income from Operations(1)


                                                                                
              
                (unaudited)


                                                                           
              
                (in thousands)




                                                                                                                                                             Three Months Ended December 31,                 Year Ended December 31,


                                                                                                                                                2024                   2023                   2024      2023





              GAAP operating expenses                                                                                                      $167,946               $151,963               $745,716  $609,092



              GAAP operating expenses includes the effect of the following
    items:



              Impairment charge(2)                                                                                                                                                       76,945



              Wind down expenses(3)                                                                                                                                                       4,971



              Non-recurring litigation related expenses                                                                                                                                   4,823



              Amortization of finite lived intangible assets acquired                                                                                               2,380                  4,759     9,519



              Acquired IPR&D5                                                                                                                                                                     18,215



              Non-GAAP operating expenses                                                                                                  $167,946               $149,583               $654,218  $581,358





              GAAP income from operations                                                                                                   $42,775                $35,029                 $9,279   $73,551



              GAAP income from operations includes the effect of the
    following items:



              Impairment charge(2)                                                                                                                                                       76,945



              Wind down expenses(3)                                                                                                                                                       4,971



              Italian payback measures4                                                                                                       5,797                                        5,797



              Non-recurring litigation related expenses                                                                                                                                   4,823



              Amortization of finite lived intangible assets acquired                                                                                               2,380                  4,759     9,519



              Acquired IPR&D5                                                                                                                                                                     18,215



              Non-GAAP income from operations                                                                                               $48,572                $37,409               $106,574  $101,285




     
     (1)See "Non-GAAP Financial Measures" for important information about our use of non-GAAP measures.



     
     (2)Represents charges associated with the impairment of the Immersive Healthcare asset group during the three months ended June 30, 2024.



     
     (3)Represents one-time expenses that include severance and other costs related to the wind down of the Immersive Healthcare business during the three months ended September 30, 2024.



     
     4Represents the impact of the Italian government's payback provision pertaining to prior years during the three months ended December 31, 2024.



     
     5Represents a one-time $18.2 million expense associated with the acquisition of IPR&D during the three months ended September 30, 2023.


                                                                                                 
              
                Penumbra, Inc.


                                                               
             
     Reconciliation of GAAP Net Income and GAAP Diluted EPS to Non-GAAP Net Income and Non-GAAP Diluted EPS(1)


                                                                                                  
              
                (unaudited)


                                                                                    
              
                (in thousands, except per share amounts)




                                                                                                                                       Three Months Ended                             Three Months Ended                  Year Ended                       Year Ended

                                                                                                                                       December 31, 2024                             December 31, 2023                  December 31, 2024                      December 31, 2023


                                                                                                                          Net                  Diluted                  Net                Diluted              Net         Diluted              Net             Diluted
                                                                                                                   income                   EPS                  income                 EPS              income          EPS              income              EPS



              GAAP net income                                                                                        $33,683                     $0.86               $54,218                   $1.38           $14,012            $0.36           $90,954                $2.32



              GAAP net income includes the effect of the
    following items:



                Italian payback measure(2)                                                                             5,797                      0.15                                                         5,797             0.15



                Impairment charge(3)                                                                                                                                                                        76,945             1.96



                Wind down expenses4                                                                                                                                                                          4,971             0.13



                Non-recurring litigation expenses                                                                                                                                                            4,823             0.12



                Amortization of finite lived intangible assets acquired                                                                                              2,380                    0.06             4,759             0.12             9,519                 0.25



                Acquired IPR&D5                                                                                                                                                                                                              18,215                 0.46



                Tax effect on the non-GAAP adjustments above6                                                        (1,217)                   (0.03)                (573)                 (0.01)         (23,387)          (0.60)          (2,293)              (0.06)



                Excess tax benefits related to stock compensation                                                      (343)                   (0.01)                (648)                 (0.02)            (837)          (0.02)          (9,020)              (0.23)
      awards



                Valuation allowance release7                                                                                                                      (25,493)                 (0.65)                                          (25,493)              (0.65)



              Non-GAAP net income                                                                                    $37,920                     $0.97               $29,884                   $0.76           $87,083            $2.22           $81,882                $2.09





              GAAP diluted EPS                                                                                                                  $0.86                                        $1.38                             $0.36                                 $2.32



              Non-GAAP diluted EPS                                                                                                              $0.97                                        $0.76                             $2.22                                 $2.09




     
     (1)See "Non-GAAP Financial Measures" for important information about our use of non-GAAP measures.



     
     (2)Represents the impact of the Italian government's payback provision pertaining to prior years during the three months ended December 31, 2024.



     
     (3)Represents charges associated with the impairment of the Immersive Healthcare asset group during the three months ended June 30, 2024.



     
     4Represents one-time expenses that include severance and other costs related to the wind down of the Immersive Healthcare business during the three months ended September 30, 2024.



     
     5Represents a one-time $18.2 million expense associated with the acquisition of IPR&D during the three months ended September 30, 2023.



     
     6For the three and twelve months ended December 31, 2024, management used a combined federal and state tax rate of 24.23% to compute the tax effect of non-GAAP measures, except for the Italian payback measure, which used a federal tax rate of 21.0%. For the three and twelve months ended December 31, 2023, management used a combined federal and state tax rate of 24.09% to compute the tax effect of non-GAAP measures.



     
     7The Company released a valuation allowance against its Federal R&D tax credits and partially released a valuation allowance against its California deferred tax assets, resulting in a tax benefit of $25.5 million during the three and twelve months ended December 31, 2023.


                                                     
              
                Penumbra, Inc.


      
              
                Reconciliation of GAAP Net Income and GAAP Net Income Margin to Adjusted EBITDA and Adjusted EBITDA Margin(1)


                                                       
              
                (unaudited)


                                         
              
                (in thousands, except for percentages)




                                                                                                                    Three Months Ended December
                                                                                                                        31,                             Year Ended December 31,


                                                                                                      2024                   2023                  2024            2023



     GAAP net income                                                                              $33,683                $54,218               $14,012         $90,954



     Adjustments to GAAP net income:



     Italian payback measure(2)                                                                     5,797                                       5,797



     Depreciation and amortization expense                                                          4,388                  7,039                23,702          27,257



     Interest income, net                                                                         (2,939)               (2,570)             (12,272)        (5,086)



     Provision for (benefit from) income taxes                                                     10,656               (16,060)                6,857        (11,304)



     Stock-based compensation expense                                                              12,095                 10,791                46,164          50,516



     Impairment charge(3)                                                                                                                     76,945



     Wind down expenses4                                                                                                                       4,971



     Non-recurring litigation related expenses                                                                                                 4,823



     Acquired IPR&D5                                                                                                                                         18,215



     Adjusted EBITDA                                                                              $63,680                $53,418              $170,999        $170,552





     GAAP revenue                                                                                $315,518               $284,679            $1,194,615      $1,058,522



     Adjusted revenue(2)                                                                         $321,315                284,679            $1,200,412      $1,058,522



     Adjusted EBITDA                                                                              $63,680                $53,418              $170,999        $170,552



     GAAP net income margin                                                                        10.7 %                19.0 %                1.2 %          8.6 %



     Adjusted EBITDA margin                                                                        19.8 %                18.8 %               14.2 %         16.1 %




     
     (1)See "Non-GAAP Financial Measures" for important information about our use of non-GAAP measures.



     
     (2)Represents the impact of the Italian government's payback provision pertaining to prior years during the three months ended December 31, 2024.



     
     (3)Represents charges associated with the impairment of the Immersive Healthcare asset group during the three months ended June 30, 2024.



     
     4Represents one-time expenses that include severance and other costs related to the wind down of the Immersive Healthcare business during the three months ended September 30, 2024.



     
     5Represents a one-time $18.2 million expense associated with the acquisition of IPR&D during the three months ended September 30, 2023.


                                                                                    
              
                Penumbra, Inc.


                                                     
       
       Reconciliation of Revenue and Adjusted Revenue Change by Geographic Regions to Adjusted Constant Currency and
                                                                                      Constant Currency Revenue Growth(1)


                                                                                      
              
                (unaudited)


                                                                        
              
                (in thousands, except for percentages)




                                                       
       
        Three Months Ended December 31,                                                                                                 Reported             Adjusted            Adjusted           Adjusted
                                                                                                                                                                                        Revenue              Revenue              FX               Constant
                                                                                                                                                                                         Change               Impact                 Impact        Currency
                                                                                                                                                                                          (%)                                        (%)            (%)
                                                                                                                                                                                                                        (%)


                                                                2024                                                                                                       2023


                            Adjusted     Adjustment               Revenue                                Adjusted                                Adjustment                     Revenue
                    Revenue                                                                   revenue


      United States         $247,917 
     $           -              $247,917                                 $203,684                   
              $           -                    $203,684                 21.7 %               - %                - %               21.7 %


      International           73,398         (5,797)                67,601                                   80,995                                                                 80,995               (16.5) %             7.1 %               0.3 %               (9.1) %



     Total                 $321,315        $(5,797)              $315,518                                 $284,679                   
              $           -                    $284,679                 10.8 %             2.1 %               0.1 %                13.0 %


                            Three Months Ended December 31,            Reported Change               FX Impact             Constant Currency Change


                       2024            2023         
           
            $           %       
       
        $        
       
            $                     %


     United States $247,917        $203,684                    $44,233       21.7 %    
       $       -               $44,233                 21.7 %


     International   67,601          80,995                   (13,394)    (16.5) %             (13)              (13,407)              (16.6) %


     Total         $315,518        $284,679                    $30,839       10.8 %            $(13)               $30,826                 10.8 %


                                                      
     
         Year Ended December 31,                                                        Reported            Adjusted             Adjusted             Adjusted
                                                                                                                                     Revenue             Revenue               FX                 Constant
                                                                                                                                      Change              Impact                  Impact          Currency
                                                                                                                                       (%)                                        (%)              (%)
                                                                                                                                                                    (%)


                                                          2024                                                          2023


                             Adjusted     Adjustment        Revenue                           Adjusted     Adjustment        Revenue
                   Revenue                                                            revenue


     United States           $902,067 
     $           -       $902,067                            $757,151 
     $          -        $757,151                19.1 %               - %                   - %               19.1 %


     International            298,345         (5,797)        292,548                             301,371                        301,371               (2.9) %             1.9 %                (0.1) %               (1.1) %


     Total                 $1,200,412        $(5,797)     $1,194,615                          $1,058,522 
     $          -      $1,058,522                12.9 %             0.5 %                    - %               13.4 %


                              Year Ended December 31,              Reported Change              FX Impact              Constant Currency Change


                         2024            2023         
     
            $                   %    
       
          $    
     
           $                             %


     United States   $902,067        $757,151             $144,916               19.1 % 
       $         -       $144,916                         19.1 %


     International    292,548         301,371              (8,823)             (2.9) %           (518)        (9,341)                       (3.1) %


     Total         $1,194,615      $1,058,522             $136,093               12.9 %          $(518)       $135,575                         12.8 %


                                                                                           
              
                Penumbra, Inc.


                                                   
          
       Reconciliation of Revenue and Adjusted Revenue Change by Product Categories and Geographic Regions to Adjusted Constant
                                                                                      Currency and Constant Currency Revenue Growth(1)


                                                                                            
              
                (unaudited)


                                                                               
              
                (in thousands, except for percentages)




                                                         
      
               Three Months Ended December 31,                                                                                                    Reported            Adjusted            Adjusted           Adjusted
                                                                                                                                                                                                   Revenue             Revenue              FX               Constant
                                                                                                                                                                                                    Change              Impact                 Impact        Currency
                                                                                                                                                                                                     (%)                                       (%)            (%)
                                                                                                                                                                                                                                  (%)


                                                                        2024                                                                                                          2023


                                    Adjusted Adjustment                   Revenue                                Adjusted                                Adjustment                        Revenue
                            Revenue                                                                   revenue


               Thrombectomy         $222,736    $(2,607)                  $220,129                                 $190,780                   
              $           -                       $190,780               15.4 %              1.4 %               0.1 %              16.9 %


               Embolization           98,579     (3,190)                    95,389                                   93,899                                                                    93,899                1.6 %              3.4 %               0.1 %               5.1 %
    and Access



              Total                $321,315    $(5,797)                  $315,518                                 $284,679                   
              $           -                       $284,679               10.8 %              2.1 %               0.1 %              13.0 %


                                     Three Months Ended December 31,           Reported Change           FX Impact            Constant Currency Change


                                2024            2023         
           
           $           %     
     
        $        
       
          $                      %


               Thrombectomy $220,129        $190,780                   $29,349       15.4 %          $65              $29,414                  15.4 %


               Embolization   95,389          93,899                     1,490        1.6 %         (78)               1,412                   1.5 %
    and Access



              Total        $315,518        $284,679                   $30,839       10.8 %        $(13)             $30,826                  10.8 %


                                                           
     
         Year Ended December 31,                                                        Reported            Adjusted            Adjusted             Adjusted
                                                                                                                                          Revenue             Revenue              FX                 Constant
                                                                                                                                           Change              Impact                 Impact          Currency
                                                                                                                                            (%)                                       (%)              (%)
                                                                                                                                                                         (%)


                                                               2024                                                          2023


                                      Adjusted Adjustment        Revenue                           Adjusted     Adjustment        Revenue
                            Revenue                                                        revenue


               Thrombectomy           $818,082    $(2,607)       $815,475                            $677,343 
     $          -        $677,343                20.4 %             0.4 %                   - %              20.8 %


               Embolization            382,330     (3,190)        379,140                             381,179                        381,179               (0.5) %             0.8 %               (0.1) %                0.2 %
    and Access



              Total                $1,200,412    $(5,797)     $1,194,615                          $1,058,522 
     $          -      $1,058,522                12.9 %             0.5 %                   - %              13.4 %


                                       Year Ended December 31,              Reported Change          FX Impact              Constant Currency Change


                                  2024            2023         
     
            $                   %  
     
          $    
     
           $                             %


               Thrombectomy   $815,475        $677,343             $138,132               20.4 %       $(77)       $138,055                         20.4 %


               Embolization    379,140         381,179              (2,039)             (0.5) %       (441)        (2,480)                       (0.7) %
    and Access



              Total        $1,194,615      $1,058,522             $136,093               12.9 %      $(518)       $135,575                         12.8 %


                                                                                     
     
     Three Months Ended December 31,                                                      Reported             Adjusted            Adjusted           Adjusted
                                                                                                                                                                      Revenue              Revenue              FX               Constant
                                                                                                                                                                       Change               Impact                 Impact        Currency
                                                                                                                                                                        (%)                                        (%)            (%)
                                                                                                                                                                                                      (%)


                                                                                         2024                                                            2023


                                                            Adjusted     Adjustment        Revenue                             Adjusted     Adjustment        Revenue
                                                    Revenue                                                            revenue



              
                Thrombectomy



               United States                               $180,647 
     $           -       $180,647                              $141,891 
     $          -        $141,891                 27.3 %               - %                - %               27.3 %



               International                                 42,089         (2,607)         39,482                                48,889                         48,889               (19.2) %             5.3 %               0.4 %              (13.5) %



               Total Thrombectomy                           222,736         (2,607)        220,129                               190,780                        190,780                 15.4 %             1.4 %               0.1 %                16.9 %


                            Embolization and Access



               United States                                 67,270                         67,270                                61,793                         61,793                  8.9 %               - %                - %                8.9 %



               International                                 31,309         (3,190)         28,119                                32,106                         32,106               (12.4) %             9.9 %               0.2 %               (2.3) %



               Total Embolization                            98,579         (3,190)         95,389                                93,899                         93,899                  1.6 %             3.4 %               0.1 %                 5.1 %
     and Access



              
                   Total                        $321,315        $(5,797)       $315,518                              $284,679 
     $          -        $284,679                 10.8 %             2.1 %               0.1 %                13.0 %


                                                          Three Months Ended December 31,                Change               FX Impact             Constant Currency Change


                                                     2024          2023         
             
           $        %      
       
        $     
          
           $                   %



           
                Thrombectomy



            United States                       $180,647      $141,891                     $38,756    27.3 %   
       $       -              $38,756               27.3 %



            International                         39,482        48,889                     (9,407) (19.2) %              65               (9,342)            (19.1) %



            Total Thrombectomy                   220,129       190,780                      29,349    15.4 %              65                29,414               15.4 %


                         Embolization and Access



            United States                         67,270        61,793                       5,477     8.9 %                                5,477                8.9 %



            International                         28,119        32,106                     (3,987) (12.4) %            (78)              (4,065)            (12.7) %



            Total Embolization and                95,389        93,899                       1,490     1.6 %            (78)                1,412                1.5 %
     Access



           
                   Total                $315,518      $284,679                     $30,839    10.8 %           $(13)              $30,826               10.8 %


                                                                                      
     
             Year Ended December 31,                                                         Reported            Adjusted            Adjusted             Adjusted
                                                                                                                                                                          Revenue             Revenue              FX                 Constant
                                                                                                                                                                           Change              Impact                 Impact          Currency
                                                                                                                                                                            (%)                                       (%)              (%)
                                                                                                                                                                                                         (%)


                                                                                              2024                                                          2023


                                                              Adjusted    Adjustment           Reported                           Adjusted     Adjustment        Reported
                                                    Revenue                               Revenue                         revenue                           Revenue



              
                Thrombectomy



               United States                                 $646,711 
     $          -           $646,711                            $509,886 
      $         -         $509,886                26.8 %               - %                  - %               26.8 %



               International                                  171,371        (2,607)            168,764                             167,457                         167,457                 0.8 %             1.5 %                 0.1 %                 2.4 %



               Total Thrombectomy                             818,082        (2,607)            815,475                             677,343                         677,343                20.4 %             0.4 %                   - %               20.8 %


                            Embolization and Access



               United States                                  255,356                           255,356                             247,265                         247,265                 3.3 %               - %                  - %                3.3 %



               International                                  126,974        (3,190)            123,784                             133,914                         133,914               (7.6) %             2.4 %               (0.2) %               (5.4) %



               Total Embolization                             382,330        (3,190)            379,140                             381,179                         381,179               (0.5) %             0.8 %               (0.1) %                 0.2 %
     and Access



              
                   Total                        $1,200,412       $(5,797)         $1,194,615                          $1,058,522 
      $         -       $1,058,522                12.9 %             0.5 %                   - %               13.4 %


                                                            Year Ended December 31,            Change                 FX Impact               Constant Currency Change


                                                       2024          2023        
      
            $           %    
       
         $       
     
            $                          %



           
                Thrombectomy



            United States                         $646,711      $509,886             $136,825       26.8 % 
       $        -           $136,825                      26.8 %



            International                          168,764       167,457                1,307        0.8 %           (77)              1,230                       0.7 %



            Total Thrombectomy                     815,475       677,343              138,132       20.4 %           (77)            138,055                      20.4 %


                         Embolization and Access



            United States                          255,356       247,265                8,091        3.3 %                             8,091                       3.3 %



            International                          123,784       133,914             (10,130)     (7.6) %          (441)           (10,571)                    (7.9) %



            Total Embolization and                 379,140       381,179              (2,039)     (0.5) %          (441)            (2,480)                    (0.7) %
     Access



           
                   Total                $1,194,615    $1,058,522             $136,093       12.9 %         $(518)           $135,575                      12.8 %




     
     (1)See "Non-GAAP Financial Measures" for important information about our use of non-GAAP measures.

Investor Relations
Penumbra, Inc.
investors@penumbrainc.com

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SOURCE Penumbra, Inc.