10x Genomics Reports Second Quarter 2025 Financial Results

PLEASANTON, Calif., Aug. 7, 2025 /PRNewswire/ -- 10x Genomics, Inc. (Nasdaq: TXG), a leader in single cell and spatial biology, today reported financial results for the second quarter ended June 30, 2025.

Recent Updates

--  Revenue was $172.9 million for the second quarter. Excluding $27.3 million related to a patent litigation settlement, revenue was $145.6 million.
--  Ended the second quarter with cash and cash equivalents and marketable securities of $447.3 million, representing a $20 million increase over the prior quarter.
--  Entered into a definitive agreement to acquire Scale Biosciences for upfront cash and stock consideration of $30 million, plus contingent consideration that could become payable upon the achievement of certain milestones. The acquisition strengthens the company's leadership in single cell analysis with key technology that will drive innovation and expand access by enabling more powerful, affordable and scalable experiments across a broader range of applications.
--  Began shipping Visium HD 3' and HD cell segmentation, expanding the Visium portfolio's capabilities by enabling high-resolution, high-sensitivity profiling across a wider range of applications.
--  Announced a partnership with the Genome Institute of Singapore on the TISHUMAP initiative, which will leverage Xenium and AI to uncover novel biomarkers and therapeutic targets for cancer and inflammatory diseases.

"The second quarter unfolded largely as anticipated," said Serge Saxonov, Co-founder and CEO of 10x Genomics. "Amid continued uncertainty in the funding environment, we're encouraged by the resilience of our business and the dedication of our team. We're focused on disciplined execution, and remain confident in the strength of our technology, the momentum behind our platforms and the significant long-term opportunity in front of us."

Second Quarter 2025 Financial Results

Revenue was $172.9 million for the second quarter of 2025. Excluding $27.3 million related to a patent litigation settlement, revenue was $145.6 million, a 5% decrease from the corresponding period of 2024, primarily driven by a decrease in instrument revenue. This figure also reflects approximately $4.0 million of revenue that resulted from customers in China accelerating purchases from the third quarter into the second quarter in anticipation of potential tariff changes.

Gross margin was 72% for the second quarter of 2025, as compared to 68% for the corresponding prior year period. The increase in gross margin was primarily due to higher license and royalty revenue and lower royalties and warranty costs, partially offset by an increase in inventory reserves and higher manufacturing costs. Excluding the impact of license and royalty revenue, gross margin was 67% for the second quarter of 2025.

Operating expenses were $95.0 million for the second quarter of 2025, a 35% decrease from $146.0 million for the corresponding prior year period. The decrease was primarily driven by a $40.7 million gain on settlement related to the litigation settlement.

Operating income was $30.1 million for the second quarter of 2025, as compared to operating loss of $41.7 million for the corresponding prior year period.

Net income was $34.5 million for the second quarter of 2025, as compared to a net loss of $37.9 million for the corresponding prior year period.

Cash and cash equivalents and marketable securities were $447.3 million as of June 30, 2025.

Third Quarter 2025 Revenue Guidance

10x Genomics expects third quarter 2025 revenue to be in the range of $140 million to $144 million. This guidance reflects approximately $4.0 million of revenue that resulted from customers in China accelerating purchases from the third quarter into the second quarter in anticipation of potential tariff changes.

Webcast and Conference Call Information

10x Genomics will host a conference call to discuss the second quarter 2025 financial results, business developments and outlook after market close on Thursday, August 7, 2025 at 1:30 PM Pacific Time / 4:30 PM Eastern Time. A webcast of the conference call can be accessed at http://investors.10xgenomics.com. The webcast will be archived and available for replay at least 45 days after the event.

About 10x Genomics

10x Genomics is a life science technology company building products to accelerate the mastery of biology and advance human health. Our integrated research solutions include instruments, consumables and software for single cell and spatial biology, which help academic and translational researchers and biopharmaceutical companies understand biological systems at a resolution and scale that matches the complexity of biology. Our products are behind breakthroughs in oncology, immunology, neuroscience and more, fueling powerful discoveries that are transforming the world's understanding of health and disease. To learn more, visit 10xgenomics.com or connect with us on LinkedIn, X, Facebook, Bluesky or YouTube.

Forward Looking Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 as contained in Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which are subject to the "safe harbor" created by those sections. All statements included in this press release, other than statements of historical facts, may be forward-looking statements. Forward-looking statements generally can be identified by the use of forward-looking terminology such as "may," "might," "will," "should," "expect," "plan," "anticipate," "could," "intend," "target," "project," "contemplate," "believe," "see," "estimate," "predict," "potential," "would," "likely," "seek" or "continue" or the negatives of these terms or variations of them or similar terminology, but the absence of these words does not mean that a statement is not forward-looking. These forward-looking statements include statements regarding 10x Genomics, Inc.'s partnerships, plans, positioning, product launches, organization, goals, opportunities, potential, specifications, costs, enthusiasm, trends and adoption of 10x Genomics, Inc.'s products and services, expected performance advantages and benefits of using 10x Genomics, Inc.'s products and services and 10x Genomics, Inc.'s financial performance and results of operations, including expectations regarding revenue and guidance as well as government policy and academic and government research funding. These statements are based on management's current expectations, forecasts, beliefs, assumptions and information currently available to management. Actual outcomes and results could differ materially from these statements due to a number of factors and such statements should not be relied upon as representing 10x Genomics, Inc.'s views as of any date subsequent to the date of this press release. 10x Genomics, Inc. disclaims any obligation to update any forward-looking statements provided to reflect any change in 10x Genomics' expectations or any change in events, conditions or circumstances on which any such statement is based, except as required by law. The material risks and uncertainties that could affect 10x Genomics, Inc.'s financial and operating results and cause actual results to differ materially from those indicated by the forward-looking statements made in this press release include those discussed under the captions "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations" in the company's most recently-filed 10-K for the fiscal year ended December 31, 2024, filed on February 13, 2025, and the company's quarterly reports on Form 10-Q for the quarter ended March 31, 2025, filed on May 9, 2025, and for the quarter ended June 30, 2025, to be filed with the Securities and Exchange Commission (SEC), and elsewhere in the documents 10x Genomics, Inc. files with the SEC from time to time.

Disclosure Information

10x Genomics uses filings with the Securities and Exchange Commission, its website (https://www.10xgenomics.com/), press releases, public conference calls, public webcasts and its social media accounts as means of disclosing material non-public information and for complying with its disclosure obligations under Regulation FD.

Contacts
Investors: investors@10xgenomics.com
Media: media@10xgenomics.com

                                                              
      
          10x Genomics, Inc.


                                                       
    
     Condensed Consolidated Statements of Operations


                                                                
        
          (Unaudited)


                                                       
    
     (In thousands, except share and per share data)




                                                                                                                           Three Months Ended             Six Months Ended
                                                                                                               
        June 30,                
 June 30,


                                                                                                                   2025               2024               2025                 2024



        Products and services revenue (1)                                                                     $145,157           $152,990           $282,980             $293,995



        License and royalty revenue (1)                                                                         27,751                114             44,811                  115



        Revenue                                                                                                172,908            153,104            327,791              294,110



        Cost of products and services revenue (2)                                                               47,824             48,884             97,262               96,976



        Gross profit                                                                                           125,084            104,220            230,529              197,134



        Operating expenses:



        Research and development (2)                                                                            61,224             62,918            125,469              131,556



        Selling, general and administrative (2)                                                                 74,434             83,039            164,162              168,813



        Gain on settlement                                                                                    (40,700)                            (49,900)



        Total operating expenses                                                                                94,958            145,957            239,731              300,369



        Income (loss) from operations                                                                           30,126           (41,737)           (9,202)           (103,235)



        Other income (expense):



        Interest income                                                                                          4,271              4,715              7,957                9,451



        Interest expense                                                                                           (3)               (1)               (3)                 (2)



        Other income (expense), net                                                                              2,603               (56)             4,739              (1,096)



        Total other income                                                                                       6,871              4,658             12,693                8,353



        Income (loss) before provision for income taxes                                                         36,997           (37,079)             3,491             (94,882)



        Provision for income taxes                                                                               2,459                818              3,311                2,964



        Net income (loss)                                                                                      $34,538          $(37,897)              $180            $(97,846)





        Net income (loss) per share, basic                                                                       $0.28            $(0.32)    
 $          -             $(0.82)



        Net income (loss) per share, diluted                                                                     $0.28            $(0.32)    
 $          -             $(0.82)



        Weighted-average shares used to compute net income                                                 123,755,409        120,066,972        123,183,924          119,461,485
(loss) per share, basic



        Weighted-average shares used to compute net income                                                 124,509,720        120,066,972        124,258,150          119,461,485
(loss) per share, diluted




 (1) The following table represents revenue by source for the periods indicated (in thousands). Spatial products includes the Company's Visium and Xenium products:

                                                       Three Months Ended                         Six Months Ended
                                          
       June 30,                
         June 30,


                                             2025            2024              2025              2024



 
        Instruments



 Chromium                                 $5,727          $8,792           $11,640           $16,642



 Spatial                                  $8,770          15,060           $17,672            32,663



 
        Total instruments revenue       14,497          23,852            29,312            49,305



 
        Consumables



 Chromium                                 85,788          94,108           169,897           178,035



 Spatial                                  36,397          29,254            67,644            55,662



 
        Total consumables revenue      122,185         123,362           237,541           233,697



 
        Services                         8,475           5,776            16,127            10,993



 
        Products and services revenue  145,157         152,990          $282,980          $293,995



 
        License and royalty revenue     27,751             114           $44,811              $115



 
        Total revenue                 $172,908        $153,104          $327,791          $294,110


 The following table presents revenue by geography based on the location of the customer for the periods indicated (in thousands):

                                                            Three Months Ended                         Six Months Ended
                                               
       June 30,                
         June 30,


                                                  2025            2024              2025              2024



 
            Americas



 United States*                              $103,491         $89,672          $190,309          $165,309



 Americas (excluding United States)             2,667           3,419            $6,419             7,412



 
            Total Americas                  106,158          93,091           196,728           172,721



 
            Europe, Middle East and Africa   34,734          37,362            66,629            72,083



 
            Asia-Pacific



 China                                         23,170          13,738            40,053            27,662



 Asia-Pacific (excluding China)                 8,846           8,913            24,381            21,644



 
            Total Asia-Pacific               32,016          22,651            64,434            49,306



 Total revenue                               $172,908        $153,104          $327,791          $294,110





 * Includes license and royalty revenue.




          (2)     Includes stock-based compensation expense as follows:

                                                      Three Months Ended                        Six Months Ended
                                         
       June 30,                
         June 30,



 
            (in thousands)               2025            2024              2025             2024



 Cost of revenue                         $1,989          $2,247            $4,470           $4,280



 Research and development                12,613          17,862            26,719           34,750



 Selling, general and administrative     12,643          18,383            27,132           35,591



 Total stock-based compensation expense $27,245         $38,492           $58,321          $74,621

                                          
         
            10x Genomics, Inc.


                                
          
           Condensed Consolidated Balance Sheets


                                             
         
            (Unaudited)


                                            
         
            (In thousands)




                                                                                                June 30, December 31,
                                                                                                    2025          2024



 
            Assets



 Current assets:



 Cash and cash equivalents                                                                     $397,712      $344,067



 Marketable securities                                                                           49,549        49,335



 Accounts receivable, net                                                                        49,977        87,862



 Other receivables                                                                               69,090           606



 Inventory                                                                                       68,968        83,107



 Prepaid expenses and other current assets                                                       20,365        19,410



 Total current assets                                                                           655,661       584,387



 Property and equipment, net                                                                    239,710       252,648



 Operating lease right-of-use assets                                                             62,700        57,290



 Goodwill                                                                                         4,511         4,511



 Intangible assets, net                                                                          14,714        15,671



 Other noncurrent assets                                                                          2,674         4,129



 Total assets                                                                                  $979,970      $918,636



 
            Liabilities and stockholders' equity



 Current liabilities:



 Accounts payable                                                                               $15,938       $12,909



 Accrued compensation and related benefits                                                       26,102        33,615



 Accrued expenses and other current liabilities                                                  39,063        41,165



 Deferred revenue                                                                                21,449        20,658



 Operating lease liabilities                                                                      9,669         9,286



 Total current liabilities                                                                      112,221       117,633



 Operating lease liabilities, noncurrent                                                         77,075        73,327



 Deferred revenue, noncurrent                                                                    11,270        12,513



 Other noncurrent liabilities                                                                     6,125         5,029



 Total liabilities                                                                              206,691       208,502



 Commitments and contingencies



 Stockholders' equity:



 Preferred stock                                                                                      -



 Common stock                                                                                         2             2



 Additional paid-in capital                                                                   2,239,924     2,177,672



 Accumulated deficit                                                                        (1,466,867)  (1,467,047)



 Accumulated other comprehensive income (loss)                                                      220         (493)



 Total stockholders' equity                                                                     773,279       710,134



 Total liabilities and stockholders' equity                                                    $979,970      $918,636

View original content to download multimedia:https://www.prnewswire.com/news-releases/10x-genomics-reports-second-quarter-2025-financial-results-302524722.html

SOURCE 10x Genomics, Inc.