Oct 6, 2017   SOURCE: PR NewsWire

DRG Expects the Pancreatic Cancer Market to Grow at an annual rate of 10% over the next 10 years to Reach Almost $4 Billion in 2026

BURLINGTON, Mass., Oct. 6, 2017 /PRNewswire/ -- Decision Resources Group finds that the pancreatic cancer market will grow from $1.3 billion in 2016 to $3.7 billion in 2026. This growth will be fueled by the increased penetration of existing branded chemotherapy agents, and the approval of novel premium-priced targeted agents for the treatment of metastatic disease.

Other key findings from the Disease Landscape & Forecast report entitled Pancreatic Cancer:

    --  Increased market penetration of current therapies: DRG anticipates an
        increase in uptake of Ipsen/Shire's Onivyde in Europe and the United
        States, and a launch in Japan in 2019 is expected. Adoption of Celgene's
        Abraxane (with gemcitabine) as the standard of care for locally advanced
        and metastatic disease is expected; we also anticipate label expansion
        in the adjuvant setting for resectable patients, and further increase in
        uptake as a backbone in upcoming combination therapies. Keytruda,
        although approved for only a small patient subpopulation, will be a
        significant contributor in second-line pancreatic cancer market.
    --  Emerging therapies for metastatic pancreatic cancer: The first-line
        setting is the most dynamic treatment setting in pancreatic cancer, and
        we expect the launch of three additional novel targeted agents in this
        space by 2026 - PEGPH20 (Halozyme's pegylated hyaluronidase),
        napabucasin (Dainippon Sumitomo's STAT3 inhibitor), and Lynparza
        (AstraZeneca's PARP inhibitor). DRG expects the launch of the
        immunotherapeutic agent - PEG-ilodecakin (ARMO Biosciences' recombinant
        pegylated interleukin-10) for the second-line treatment of pancreatic
        cancer.
    --  The pancreatic neuroendocrine tumors market: The recent approval of
        Ipsen/Teijin's Somatuline Autogel in Japan will increase the value of
        the overall pancreatic cancer therapy market. However, the small PNETs
        market will decline in value, and its share of the overall pancreatic
        cancer market will depreciate from 13% in 2016 to 4% in 2026, primarily
        due to the generic erosion of the major players - Ipsen/Teijin's
        Somatuline Autogel (lanreotide extended-release), Novartis's Afintior
        (everolimus), and Pfizer's Sutent (sunitinib), and the lack of new
        product launches in the forecast period.
    --  Declining market value after 2024: The already-highly genericized
        pancreatic cancer market will see a decline in growth after 2024 due to
        the generic erosion of most important players; this value decline is
        unlikely to be offset by the emerging therapies.

Comments from Decision Resources Group Analyst Anamika Ghosh, PhD:

    --  "Approval of PEGPH20 is highly anticipated. It will be the first-ever
        targeted therapy to receive approval for the treatment of first-line
        metastatic pancreatic cancer. It is set to be the forerunner of
        biomarker-based stratification in pancreatic cancer as the therapy has
        shown impressive clinical results in patients with high levels of
        hyaluronan."
    --  "Lynparza is expected to pave a new path in medical practice for
        pancreatic by introducing the concept of maintenance therapy to
        pancreatic cancer. Although the therapy will benefit only a very small
        patient subpopulation - only patients with gBRCA mutation that respond
        to platinum-based first-line therapy - this will still be a huge leap in
        the treatment of pancreatic cancer."

Additional Resources:

    --  Anamika Ghosh has written a blog on the subject, which can be found
        here.

For more information on purchasing this report, please visit our website.

About Decision Resources Group
DRG, a subsidiary of Piramal Enterprises Ltd., is the premier source for global healthcare data and market intelligence. A trusted partner for over 20 years, DRG helps companies competing in the global healthcare industry make informed business decisions. Organizations committed to the developing and delivering life-changing therapies to patients rely on DRG's in-house team of expert healthcare analysts, data scientists, and consultants for critical guidance. DRG products and services, built on extensive data assets and delivered by experts, empower organizations to succeed in complex healthcare markets.

Media contact:

Decision Resources Group
Stephanie Cooper
212-414-7570
scooper@dresources.com

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SOURCE Decision Resources Group