Gastroparesis Drugs Market to Grow by USD 1.34 Billion (2025-2029), Driven by Rising Global Diabetes Burden, AI's Role in Market Transformation - Technavio

NEW YORK, Jan. 21, 2025 /PRNewswire/ -- Report with the AI impact on market trends - The global gastroparesis drugs market size is estimated to grow by USD 1.34 billion from 2025-2029, according to Technavio. The market is estimated to grow at a CAGR of 3.5% during the forecast period. Rising global burden of diabetes is driving market growth, with a trend towards increasing growth opportunities in emerging markets. However, stringent regulatory guidelines poses a challenge. Key market players include Abbott Laboratories, AbbVie Inc., Aclipse Therapeutics, ANI Pharmaceuticals Inc., Bausch Health Companies Inc., Cadila Pharmaceuticals Ltd., Eisai Co. Ltd., Evoke Pharma Inc., GlaxoSmithKline Plc, Ipca Laboratories, Johnson and Johnson Inc., Medtronic Plc, Neurogastrx Inc., Otsuka Pharmaceutical Co. Ltd., Pfizer Inc., Processa Pharmaceuticals Inc., Rhythm Pharmaceuticals Inc., Takeda Pharmaceutical Co. Ltd., Theravance Biopharma Inc., and Vanda Pharmaceuticals Inc..

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              Gastroparesis Drugs Market Scope



     Report Coverage                             
      Details



     Forecast period                             
      2025-2029



     Base Year                                                                                                                                             2024



     Historic Data                               
      2019 - 2023



     Segment Covered                                Drug Class (Prokinetic agents, Antiemetics, and Botulinum toxin injection), Disease Type (Idiopathic
                                                      gastroparesis, Diabetic gastroparesis, and Post-surgical gastroparesis), Geography (North America, Europe,
                                                      Asia, and Rest of World (ROW)), Drug, and Route of Administration.



     Region Covered                              
      North America, Europe, Asia, and Rest of World (ROW)


                                                    Abbott Laboratories, AbbVie Inc., Aclipse Therapeutics, ANI Pharmaceuticals Inc., Bausch Health Companies
                                                      Inc., Cadila Pharmaceuticals Ltd., Eisai Co. Ltd., Evoke Pharma Inc., GlaxoSmithKline Plc, Ipca
                                                      Laboratories, Johnson and Johnson Inc., Medtronic Plc, Neurogastrx Inc., Otsuka Pharmaceutical Co. Ltd.,
                                                      Pfizer Inc., Processa Pharmaceuticals Inc., Rhythm Pharmaceuticals Inc., Takeda Pharmaceutical Co. Ltd.,

     Key companies profiled                          Theravance Biopharma Inc., and Vanda Pharmaceuticals Inc.

Key Market Trends Fueling Growth

The Gastroparesis market is witnessing significant growth due to the rising prevalence of gastroparesis, particularly in diabetes patients and those with lifestyle factors like alcohol consumption and tobacco use. Neurogastrx's tradipitant and ANI Pharmaceuticals' metopimazine are innovative drugs gaining attention for their effectiveness in symptom management, including nausea, vomiting, and abdominal discomfort. Evoke Pharma's motilin receptor agonist, relamorelin, is another promising treatment. FDA clearance for these drugs and others, such as deudomperidone and metoclopramide, continues to drive market expansion. Diabetic gastroparesis cases, often linked to blood sugar regulation and nutrient absorption complications, are a major focus. Hospitals and specialized care centers offer surgical interventions like gastrojejunostomy and enteral nutrition for severe cases. PubMed Central reports ongoing clinical trials for prokinetic agents, including Erythromycin and antiemetics like Reglan, to hinder digestion further. Acute conditions like cholecystitis and pancreatitis can also cause gastroparesis, adding to the market's complexity.

Vendors in the gastrointestinal drugs market are expanding their businesses in emerging economies to tap into the growing number of people with undiagnosed and untreated gastrointestinal disorders. For instance, the incidence and prevalence of chronic gastrointestinal disorders, such as gastroparesis, in Asia, particularly in China and India, have been increasing. To capitalize on this trend, companies are expanding their research and development teams and manufacturing facilities in these regions. Abbott, for example, is continuously growing its presence in emerging markets like Brazil, India, and China. This expansion will enable vendors to improve their existing product offerings and launch new ones, creating significant growth opportunities for the market.

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Market Challenges

    --  The Gastroparesis market faces challenges due to the complex nature of
        the condition, which involves the hindering of digestion in the stomach.
        Neurogastrx, a company specializing in gastroparesis treatments, is
        developing innovative drugs like tradipitant and metopimazine to manage
        symptoms such as nausea, vomiting, and abdominal discomfort. ANI
        Pharmaceuticals and Evoke Pharma also offer metoclopramide and
        deudomperidone, respectively. Diabetes, lifestyles factors like alcohol
        consumption and tobacco use, and surgical procedures are common causes
        of gastroparesis. Diabetic cases are particularly challenging, leading
        to complications in blood sugar regulation and nutrient absorption. FDA
        clearance for new prokinetic agents is crucial for addressing these
        needs. GI symptoms, such as those seen in Acute cholecystitis and Acute
        pancreatitis, can also contribute to gastroparesis. Erythromycin and
        antiemetics like Reglan are currently used, but clinical trials for
        newer treatments are ongoing. Autonomic neuropathy is another factor,
        requiring specialized care in hospitals and surgical interventions.
        PubMed Central provides valuable information on gastroparesis research.
    --  Regulatory authorities, such as the US Food and Drug Administration
        (FDA) and the European Medicines Agency (EMA), closely monitor drug
        development and approval processes to ensure drug sterility and
        consistency. Safety, efficacy, pharmacological data, pharmacodynamic
        effects, and drug interactions are key factors examined. Failure to meet
        these criteria may result in a Complete Response Letter (CRL) or
        rejection. Applicants receiving a CRL must provide additional data to
        address concerns. Stringent regulations ensure the highest standards in
        gastroparesis drugs market.

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Segment Overview

This gastroparesis drugs market report extensively covers market segmentation by

    1. Drug Class
        --  1.1 Prokinetic agents
        --  1.2 Antiemetics
        --  1.3 Botulinum toxin injection
    2. Disease Type
        --  2.1 Idiopathic gastroparesis
        --  2.2 Diabetic gastroparesis
        --  2.3 Post-surgical gastroparesis
    3. Geography
        --  3.1 North America
        --  3.2 Europe
        --  3.3 Asia
        --  3.4 Rest of World (ROW)
    4. Drug
    5. Route of Administration

1.1 Prokinetic agents- Prokinetic drugs play a crucial role in managing gastroparesis, a condition characterized by delayed stomach emptying. These medications, such as metoclopramide and domperidone, address the fundamental issue of stomach motility impairment. While they may not always produce a proportional improvement in stomach emptying, they are widely used due to their effectiveness in alleviating symptoms like nausea, vomiting, and early satiety. Additionally, some prokinetic agents, like metoclopramide, possess antiemetic properties. Newer drugs, including ghrelin, motilin, 5-HT4 receptor agonists, and dopamine receptor modulators, are under investigation for their potential in gastroparesis treatment. Constipation, a common complication of decreased distal gastrointestinal motility, can be challenging for patients. Prokinetic medicines, which can induce bowel movements and alleviate symptoms, will drive market growth for these agents during the forecast period. Ani Pharmaceuticals offers Reglan (metoclopramide) in the US for gastroparesis treatment.

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Research Analysis

Gastroparesis is a digestive disorder characterized by delayed emptying of the stomach. Neurogastrx's tradipitant is a promising new drug for gastroparesis treatment, showing effectiveness in clinical trials. Other drugs used for symptom management include metopimazine, deudomperidone, and metoclopramide. Evoke Pharma and ANI Pharmaceuticals are among the companies developing innovative drugs for gastroparesis. Risk factors for gastroparesis include diabetes, lifestyles (poor diet, alcohol consumption, tobacco consumption), and certain medications like Erythromycin. Symptoms include nausea, vomiting, and various GI disruptions. Potential complications include liver injury, GI bleeding, acute cholecystitis, and acute pancreatitis. Antiemetics like Reglan have been used historically, but their long-term use can lead to serious side effects. Clinical trials are ongoing to find safer and more effective treatments for gastroparesis.

Market Research Overview

Gastroparesis is a chronic condition characterized by delayed emptying of the stomach, leading to various GI symptoms such as nausea, vomiting, and abdominal discomfort. Neurogastrx's tradipitant is a promising innovative drug for gastroparesis treatment, while metopimazine, deudomperidone, and metoclopramide are commonly used prokinetic agents. Diabetes, lifestyles (alcohol consumption, tobacco consumption), and surgical procedures are known gastroparesis triggers. Diabetic gastroparesis affects a significant number of diabetic cases, leading to nutrient absorption complications and blood sugar regulation issues. FDA clearance for new gastroparesis drugs is crucial, with Evoke Pharma and ANI Pharmaceuticals being recent approvals. Other treatments include enteral nutrition, feeding intolerance management, and surgical interventions for severe cases. PubMed Central hosts numerous clinical trials on gastroparesis, exploring new treatments and understanding its causes, including autonomic neuropathy, Acute cholecystitis, Acute pancreatitis, and Erythromycin. Antiemetics and Reglan are also used for symptom management.

Table of Contents:

1 Executive Summary
2 Market Landscape
3 Market Sizing
4 Historic Market Size
5 Five Forces Analysis
6 Market Segmentation

    --  Drug Class
        --  Prokinetic Agents
        --  Antiemetics
        --  Botulinum Toxin Injection
    --  Disease Type
        --  Idiopathic Gastroparesis
        --  Diabetic Gastroparesis
        --  Post-surgical Gastroparesis
    --  Geography
        --  North America
        --  Europe
        --  Asia
        --  Rest Of World (ROW)
    --  Drug
    --  Route of Administration

7 Customer Landscape
8 Geographic Landscape
9 Drivers, Challenges, and Trends
10 Company Landscape
11 Company Analysis
12 Appendix

About Technavio

Technavio is a leading global technology research and advisory company. Their research and analysis focuses on emerging market trends and provides actionable insights to help businesses identify market opportunities and develop effective strategies to optimize their market positions.

With over 500 specialized analysts, Technavio's report library consists of more than 17,000 reports and counting, covering 800 technologies, spanning across 50 countries. Their client base consists of enterprises of all sizes, including more than 100 Fortune 500 companies. This growing client base relies on Technavio's comprehensive coverage, extensive research, and actionable market insights to identify opportunities in existing and potential markets and assess their competitive positions within changing market scenarios.

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UK: +44 203 893 3200
Email: media@technavio.com
Website: www.technavio.com/

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SOURCE Technavio