The American Diabetes Association Announces 2025 Pathway to Stop Diabetes Grant Recipients

ARLINGTON, Va., Feb. 11, 2025 /PRNewswire/ -- Today, the American Diabetes Association® (ADA) announced the awardees of the 2025 Pathway to Stop Diabetes® (Pathway) grants. This year's grants dedicate more than $6.1 million to support breakthroughs in translation and clinical science, technology, care, and potential cures in the field of diabetes.

Through the Pathway program, talented early-career scientists who demonstrate exceptional innovation, creativity, and productivity receive five to seven years of funding to explore new ideas without traditional project constraints. They are also paired with world-renowned diabetes scientists who offer mentorship as well as scientific and professional guidance throughout the duration of their grant.

This year, Pathway grants have been awarded to the following researchers and their breakthrough projects:

    --  Ilia Droujinine, PhD, assistant professor at the Scripps Research
        Institute
        --  Droujinine received the Pathway grant for his research, Decoding and
            Validating Interorgan Communication Proteins as New Therapeutic
            Targets in Diabetes, which seeks to discover systemic metabolic
            mechanisms in type 2 diabetes and the potential of
            intestine-secreted proteins as therapy for type 2 diabetes and its
            complications.
        --  "How does muscle talk to fat? How does the intestine talk to the
            brain? I believe that unraveling the intricate network of
            communication between organs is key to understanding and treating
            diabetes. I am grateful for the support of the American Diabetes
            Association Pathway to Stop Diabetes Accelerator Award, which will
            allow my lab to identify the secreted mediators driving this
            interorgan dialogue, unlocking new therapeutic opportunities for
            diabetes management," said Droujinine.
    --  Rachel Goode, PhD, MPH, MSW, Wallace Kuralt Early Career Distinguished
        Scholar associate professor at the University of North Carolina at
        Chapel Hill School of Social Work
        --  Goode received a grant for her work, Preventing Type 2 Diabetes in
            Black Adult Women At-Risk for Binge-Eating Disorder. The research
            will inform, create and pilot an individually tailored program to
            reduce binge eating and prevent weight gain in emerging adulthood as
            a pathway to reducing type 2 diabetes risk in Black women.
        --  "I am excited to have the opportunity to focus on advancing the
            science on the prevention of diabetes in a group that is
            persistently underserved--Black emergent adults. Young adults are on
            track to be diagnosed with type 2 diabetes at record levels. I am
            looking forward to the time, support, and guidance this award will
            provide to equip me to move forward to help this next generation
            avoid this pending threat," said Goode.
    --  Daniel "Dan" Seung Kim, MD, PhD, MPH, cardiovascular medicine fellow at
        Stanford University
        --  Kim's research, Integration of a trained language model to improve
            glycemic control through increased physical activity: a fully
            digital My Heart Counts smartphone app randomized trial, builds on
            his prior work-- a large-scale digital trial conducted via the My
            Heart Counts (MHC) app, which found that personalized e-coaching
            interventions increased step count.
        --  "My research focuses on increasing exercise as a medium to improve
            glycemic control via a smartphone application (My Heart Counts) that
            autonomously generates text-based coaching messages. Through the
            technological development funded by the American Diabetes
            Association, the My Heart Counts smartphone application will "learn"
            from a user's response to coaching messages and tailor future
            text-based prompts to better account for an individual's
            psychological profile (e.g., what type of coaching personality they
            prefer) and activity patterns (e.g., when are they most likely to
            exercise). This will ultimately result in an "exercise coach on the
            smartphone", tailored to each individual patient, working to combat
            the immense morbidity and mortality caused by diabetes," said Kim.
    --  David Merrick, MD, PhD, assistant professor of medicine in the division
        of endocrinology, diabetes, and metabolism at the Perelman School of
        Medicine at the University of Pennsylvania
        --  Merrick's research, Optogenetic stimulation of thermogenic adipose
            as a novel cell therapy for obesity and metabolic disease, seeks to
            fill a gap in current obesity therapies by focusing on increasing
            energy expenditure.
        --  "GLP-1 therapeutics have revolutionized the medical management of
            diabetes and obesity, primarily through the reduction of caloric
            intake. However, these medications do not significantly enhance
            energy expenditure and are prohibitively expensive as a lifelong
            weight maintenance solution. We propose to address this healthcare
            challenge with the innovation of a novel, light-inducible
            thermogenic adipose cell-therapy to compliment GLP-1 treatment by
            augmenting energy expenditure and promoting the long-term
            maintenance of weight loss and blood sugar control," said Merrick.

The Pathway program is one of many ways the ADA is investing in advancing diabetes research and clinical practice. Currently the ADA manages a portfolio of more than 190 active research awards, including 51 new projects funded in 2024. Additional information about the ADA's research findings and ongoing areas of study is available in the ADA's 2024 Research Report.

About the American Diabetes Association
The American Diabetes Association (ADA) is the nation's leading voluntary health organization fighting to end diabetes and helping people thrive. For 84 years, the ADA has driven discovery and research to prevent, manage, treat, and ultimately cure diabetes. There are 136 million Americans living with diabetes or prediabetes. Through advocacy, program development, and education, we're fighting for them all. To learn more or to get involved, visit us at diabetes.org or call 1-800-DIABETES (800-342-2383). Join us in the fight on Facebook (American Diabetes Association), Spanish Facebook (Asociación Americana de la Diabetes), LinkedIn (American Diabetes Association), and Instagram (@AmDiabetesAssn). To learn more about how we are advocating for everyone affected by diabetes, visit us on X (@AmDiabetesAssn).

Contact: Virginia Cramer
press@diabetes.org

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SOURCE American Diabetes Association