Targovax ASA: Second Quarter and First Half Year 2018 Results
OSLO, Norway, Aug 23, 2018 /PRNewswire/ -- Targovax ASA (OSE: TRVX), a clinical stage biotechnology company developing immune activators to target hard to treat solid tumors, today announces its second quarter and first half year 2018 results.
A meeting for investors, analysts and press will take place in Oslo today at 10:00 CET (details below).
HIGHLIGHTS FOR THE SECOND QUARTER AND FIRST HALF YEAR 2018
-- In January, Targovax announced that ONCOS-102 generated immune
activation at both the systemic and lesional levels in checkpoint
inhibitor (CPI) refractory melanoma in four out of the first four
patients treated
-- In February, Targovax announced that the safety lead-in part of its
ONCOS-102 trial in unresectable, malignant, pleural mesothelioma was
completed without any safety concerns, and that ONCOS-102 generates
early immune activation in treated patients
-- In May, an early signal of efficacy was reported from the ONCOS-102
phase I/II trial in mesothelioma, with activity observed in three out of
six patients in the safety lead-in cohort. The trial has now entered the
randomized phase II part, enrolling 24 more patients
-- In May, survival data was reported from the 32-patient phase I/II
clinical trial evaluating TG01 in resected pancreatic cancer in
combination with gemcitabine chemotherapy. Median overall survival for
the patients vaccinated with TG01 was 33.4 months, compared with 27.6
months for gemcitabine alone reported in the ESPAC4 trial
-- In June, the Company updated its business strategy, strengthening the
development focus on the ONCOS oncolytic virus program, with ONCOS-102
as the lead product candidate
-- In June, Targovax was granted a product patent in the EU for TG02, the
2nd generation product from the mutant-RAS neoantigen vaccine platform
-- In April, Dr. Catherine A. Wheeler was elected as a new member of the
Board of Directors
POST-PERIOD HIGHLIGHTS
-- In July, Ludwig Cancer Research and CRI announced the completion of the
safety evaluation for the first dose cohort in the phase I/II trial of
ONCOS-102 in combination with MedImmune's checkpoint inhibitor Imfinzi®
(durvalumab)
-- In July, Targovax and SOTIO announced that the first patient was dosed
in the phase I/II combination trial of ONCOS-102 with DCVAC, a dendritic
cell immune-therapy
Øystein Soug, CEO said: "It has been an exciting first half of 2018 for the oncolytic virus field. Clinical data, both from Targovax and others, have reinforced the scientific foundation of oncolytic viruses as an important class of immune activators. Oncolytic virus therapies have been further highlighted by recent deal activity in the space. Therefore, it is natural for Targovax to strengthen its efforts on the ONCOS program. We look forward to several upcoming data read-outs within the next year. We continue to see potential in the TG neo-antigen cancer vaccine to treat mutant RAS cancers, and are working closely with our scientific advisors to devise an updated strategy for how to best create value for both patients and shareholders. We aim to announce a revised development plan for the TG program during the autumn."
Presentation
The presentation will take place at 10:00 CET at:
Hotel Continental
Stortingsgaten 24/26
0117 Oslo
The presentation will also be webcast live and can be accessed through www.targovax.com.
Reporting material
Targovax second quarter and first half 2018 report
Targovax second quarter and first half 2018 presentation
The quarterly report and presentation are also available at the website www.targovax.com.
For further information, please contact:
Renate Birkeli
Investor Relations
Phone: +47-922-61-624
Email: renate.birkeli@targovax.com
Media and IR enquires:
Andreas Tinglum - Corporate Communications (Norway)
Phone: +47-9300-1773
Email: andreas.tinglum@corpcom.no
Simon Conway/Stephanie Cuthbert - FTI Consulting (International)
Phone: +44-20-3727-1000
Email: Targovax@fticonsulting.com
This information was brought to you by Cision http://news.cision.com
The following files are available for download:
http://mb.cision.com/Public/17093/2598847/b6e92fb072f0f891.pdf Targovax second quarter and
first half 2018 report
http://mb.cision.com/Public/17093/2598847/ba46e09249a958d0.pdf Targovax second quarter and
first half 2018 presentation
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SOURCE Targovax
