Global Ulcerative Colitis Drug Forecast and Market Analysis Report, 2019-2029 - The R&D Within this Space Consists of 10 Late-stage Pipeline Drugs with Five Oral Formulations
DUBLIN, Jan. 14, 2021 /PRNewswire/ -- The "Ulcerative Colitis - Global Drug Forecast and Market Analysis to 2029" report has been added to ResearchAndMarkets.com's offering.
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The current UC market is overcrowded with cheap generic drugs for mild to moderate disease, expensive biologics such as anti-tumor necrosis factors (TNFs) and anti-integrins, and biosimilars for severe disease that are used as short- or long-term alternatives to surgical options.
The R&D within this space consists of 10 late-stage pipeline drugs with five oral formulations, more convenient dosing frequencies, novel mechanisms of action (MOAs), and improved safety profiles and drug availability.
However, the pipeline products will be challenged by the increasing emergence of biosimilars, since the major brands will experience patent cliffs throughout the forecast period. Furthermore, all but one drug are being developed for moderate to severe UC, which will result in a crowded market.
This model covers the market forecast for the marketed and late-stage pipeline UC therapeutics. The model segments patients by severity, with mild-moderate, moderate-severe, and severe/fulminant segments. The base year of this model is 2019, and the forecast period is 2020-2029.
Key Questions Answered
-- Which unmet needs are limiting the treatment of ulcerative colitis in
the 8MM?
-- What strategies can the pharmaceutical industry employ to increase
treatment rates for ulcerative colitis? How should these strategies
differ across different geographical markets?
-- What effect will the launch of biosimilars and generics have on the
sales of branded agents?
-- What are the main R&D trends in the ulcerative colitis market and which
companies are leading the way? Are there major differences in the
mechanisms of action used by therapies in late-stage versus early-stage
clinical development?
Key Highlights
-- The greatest drivers of growth in the global UC market include the
launch of 10 new pipeline therapies during the forecast period and an
increasing diagnosed prevalence in many 8MM countries.
-- The main barriers to growth in the UC market include the crowded and
competitive market as well as patent expiration of key biologic brands
with subsequent biosimilar launch.
-- Novel drug classes in the UC pipeline include IL-23 inhibitors and S1P
receptor modulators. In addition, Takeda will launch a subcutaneous
version of their product, Entyvio, and two additional JAK inhibitors are
expected to make their appearance on the market.
-- The most important unmet needs in the UC market are for safer and more
effective therapies, an improvement in management of fulminant patients,
biomarkers to predict responsiveness to therapy, and standardization of
patient-reported outcomes.
Scope
-- Overview of UC including epidemiology, etiology, pathophysiology,
symptoms, diagnosis, and treatment guidelines.
-- Topline UC market revenue, annual cost of therapy, and major pipeline
product sales in the forecast period.
-- Key topics covered include current treatment and pipeline therapies,
unmet needs and opportunities, and the drivers and barriers affecting UC
therapeutics sales in the 8MM.
-- Pipeline analysis: Comprehensive data split across different phases,
emerging novel trends under development, and detailed analysis of
late-stage pipeline drugs.
-- Analysis of the current and future market competition in the global UC
therapeutics market. Insightful review of the key industry drivers,
restraints and challenges. Each trend is independently researched to
provide qualitative analysis of its implications.
Reasons to Buy
-- Develop and design your in-licensing and out-licensing strategies, using
a detailed overview of current pipeline products and technologies to
identify companies with the most robust pipelines.
-- Develop business strategies by understanding the trends shaping and
driving the global UC therapeutics market.
-- Drive revenues by understanding the key trends, innovative products and
technologies, market segments, and companies likely to impact the global
UC market in the future.
-- Formulate effective sales and marketing strategies by understanding the
competitive landscape and by analyzing the performance of various
competitors.
-- Identify emerging players with potentially strong product portfolios and
create effective counter-strategies to gain a competitive advantage.
-- Track drug sales in the global UC therapeutics market from 2019-2029.
Key Topics Covered:
1 Tables & Figures
2 Ulcerative Colitis: Executive Summary
2.1 Large Growth is Expected for UC Market from 2019-2029
2.2 Competition and Biosimilar Threat Defines UC Market
2.3 Pipeline Products Partially Address Unmet Needs
2.4 Opportunities for Managing Severe/Fulminant Patients Remain
2.5 Subcutaneous Biologics and Oral Therapies to Drive Growth in UC Market
2.6 What Do Physicians and Payers Think?
3 Introduction
3.1 Catalyst
3.2 Related Reports
3.3 Upcoming Related Reports
4 Disease Overview
4.1 Etiology and Pathophysiology
4.2 Classification or Staging Systems
4.3 Symptoms
4.4 Quality of Life
5 Epidemiology
5.1 Disease Background
5.2 Risk Factors and Comorbidities
5.3 Global and Historical Trends
5.4 Forecast Methodology
5.5 Epidemiological Forecast for UC (2019-2029)
5.6 Discussion
6 Disease Management
6.1 Diagnosis and Treatment Overview
6.2 Treatment Overview
6.3 Treatment Guidelines and Leading Prescribed Drugs
6.4 US
6.5 5EU
6.6 Japan
6.7 Canada
7 Competitive Assessment
7.1 Overview
7.2 KOL and Payer Opinion on the Impact of COVID-19
8 Unmet Needs and Opportunity Assessment
8.1 Overview
8.2 Lack of Safe and Efficacious Treatment Alternatives
8.3 Improved Medical Management for Severe/Fulminant Patients
8.4 Biomarkers to Predict Responsiveness to Therapy and Prognosis
8.5 Standardization of Patient-Reported Outcomes
9 Pipeline Assessment
9.1 Overview
9.2 Promising Drugs in Clinical Development
10. Current and Future Players
10.1 Overview
10.2 Trends in Corporate Strategy
10.3 Johnson & Johnson
10.4 AbbVie
10.5 Takeda
10.6 Pfizer
10.7 Eli Lilly
10.8 EA Pharma
10.9 Galapagos
10.10 Bristol-Myers Squibb
10.11 Arena Pharmaceuticals
11. Market Outlook
11.1 Global Markets
11.2 US
11.3 5EU
11.4 Japan
11.5 Canada
For more information about this report visit https://www.researchandmarkets.com/r/1q6b29
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