Evogene Reports First Quarter 2024 Financial Results

Conference call and webcast: today, May 23, 2024, 9:00 am ET

Financial and Business Highlights:

    --  Q1 2024 revenue: $4.2M vs. $0.6M in Q1 2023; anticipating continued
        growth in 2024.
    --  Q1 2024 net loss: $3.8M vs. $7.0M in Q1 2023.
    --  Projected 2024 cash usage, excluding Lavie Bio and Biomica: $8.0M, down
        36% from $12.5M in 2023.
    --  Ceasing Canonic's operations results in annualized savings of
        approximately $1.5 million.
    --  Casterra's new agreements with African and Brazilian castor seed growers
        secure 900 tons of castor seeds, expected to fulfill all standing orders
        by end of 2024.
    --  Biomica to present preliminary Phase 1 clinical trial results for BMC128
        at the 2024 ASCO conference on June 3.
    --  Lavie Bio received $2.5M, the second half of advanced payment from
        Corteva; announced new collaboration with Syngenta for bio insecticides;
        extended trials with Bayer for bio fungicides. Marketing and sales for
        Yalos(TM) are expanding in the US and Canada, with more crops added.
    --  AgPlenus announced a new collaboration with Bayer, including an upfront
        payment, research funding, milestone payments, and future royalties;
        achieved a milestone with Corteva in an existing collaboration
        agreement.

REHOVOT, Israel, May 23, 2024 /PRNewswire/ -- Evogene Ltd. (Nasdaq: EVGN) (TASE: EVGN), a leading computational biology company aiming to revolutionize the development of life-science-based products, today announced its financial results for the first quarter period ended March 31, 2024.

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Mr. Ofer Haviv, Evogene's President and CEO, stated: "Evogene's mission is to direct and accelerate the development of life-science based products. During the past years we developed three innovative AI tech-engines addressing the main development challenges of 3 life-science based product categories:

    --  MicroBoost AI - for the development of microbe-based products,
    --  ChemPass AI - for small-molecule-based products, and
    --  GeneRator AI - for products based on genetic elements.

Our AI tech-engines were structured to be compatible with the tremendous potential of various market segments and not limited to only one specific segment.

In order to capture the value of our AI tech-engines, our business strategy is to establish diverse collaborative partnerships through licensing or collaboration, with expert partners in specific fields that complement our technology. Together, we'll develop novel products, aiming for full or partial ownership upon project completion.

This approach maximizes the potential of our AI tech-engines, while reducing financial and development risks. We believe this strategy holds the potential for groundbreaking innovations and significant financial gains for Evogene.

Today, Evogene has 4 subsidiary companies, and diverse engagements with leading companies in additional market segments, not covered by our subsidiaries.

I am very pleased to share with you the main achievements made by Evogene and its subsidiaries from the beginning of the year."

Evogene Updates:

    --  Ceasing Canonic's operation - Evogene has decided to cease its
        subsidiary Canonic, which specialized in customized medical cannabis
        products, following challenging market conditions in the medical
        cannabis sector. This decision results in annualized savings of
        approximately $1.5 million. Resources will be reallocated to areas with
        greater growth potential, such as funding Casterra's needs for on-going
        capital.

    --  Establishment of Finally Foods - In March 2024, Evogene and The Kitchen
        FoodTech Hub by Strauss Group, established Finally Foods Ltd., an
        AI-driven company focused on sustainable protein production in plants,
        for the food sector. Finally Foods will leverage Evogene's AI technology
        to modify plants for efficient protein production. The company has
        secured pre-seed funding from TKH and the Israeli Innovation Authority.
        Evogene holds approximately 40% stake in the company.

    --  Collaboration with Verb Biotics - In February 2024, Evogene and Verb
        Biotics entered into a collaboration agreement to advance probiotic
        innovation by developing new strains of probiotic bacteria that produce
        sustainable quantities of microbial metabolites, which enhance human
        health and vitality. The partnership will leverage Evogene's MicroBoost
        AI tech-engine and Verb Biotics' expertise in microbiome health.

Subsidiaries Updates:

Casterra Ag Ltd. - focuses on developing an integrated solution to enable large-scale commercial cultivation of castor to address the global demand for stable castor oil supply, mainly for the biodiesel industry. Casterra is utilizing GeneRator AI tech engine to direct and accelerate the development of its unique elite castor seed varieties.

    --  Under the supervision of Casterra's new CEO, the company has recently
        engaged with castor seed growers in Africa and Brazil. These engagements
        are expected to yield approximately 900 tons of castor seeds in 2024,
        fulfilling all existing purchase orders and providing additional
        inventory later this year. The balance of the existing purchase orders
        is anticipated to be delivered in the second half of 2024.

Biomica Ltd. - a clinical-stage biopharmaceutical company developing innovative microbiome-based therapeutics, utilizing Evogene's MicroBoost AI tech-engine.

    --  In January, 2024, Biomica reached a significant milestone by completing
        Phase I trial enrollment for its microbiome-based immuno-oncology drug
        BMC128 - a rationally designed consortia of 4 bacteria. Biomica recently
        announced that it will be presenting preliminary Phase 1 study data of
        BMC128 in a poster presentation at the 2024 ASCO Annual Conference, on
        June 3rd.
    --  Biomica is now preparing for advancing to Phase 2 of BMC128 clinical
        trial, and already conducted a pre-IND meeting with the FDA, aiming to
        initiate Phase 2 in 2025.
    --  Results from Biomica's pre-clinical study in the IBS program, conducted
        in collaboration with NYU's medical school, were presented at the
        Digestive Disease Week 2024 Annual Conference in May 2024.

Lavie Bio Ltd. - a leading ag-biologicals company that develops microbiome-based, computational-driven novel bio-stimulant and bio-pesticide products, utilizing Evogene's MicroBoost AI tech-engine.

    --  In February, 2024, Lavie Bio announced that it had met the requirements
        of its licensing agreement for LAV311 & LAV312 with Corteva. This
        achievement enabled the successful receipt of the second half of an
        advanced payment, amounting to $2.5 million, bringing the total to $5
        million.
    --  In February, 2024, Lavie Bio signed an agreement with Syngenta for the
        development of new biological insecticidal solutions.
    --  Lavie Bio has extended its joint validation trials with Bayer for its
        bio-fungicides, following successful laboratory and greenhouse testing.
        This joint effort, aimed at combating diseases affecting fruits and
        vegetables globally, has moved to field experiments for further
        validation.
    --  In March, 2024, Lavie Bio partnered with Ceres Global Ag Corp. to
        integrate its bio-inoculant, Yalos((TM)), into regenerative agriculture
        programs across North America. This announcement and other marketing and
        sales efforts support the penetration of Yalos((TM)) in US and Canada
        markets with additional crops being added for treatment. Based on
        initial orders and sales projections, 2024 revenues are anticipated to
        increase compared to the previous year.

AgPlenus Ltd. - a global leader in computational design and development of novel sustainable crop protection products, utilizing Evogene's ChemPass AI tech-engine.

    --  In February, 2024, AgPlenus announced a licensing and collaboration
        agreement with Bayer to develop a novel mode of action broad-spectrum
        herbicide targeting the APTH1 protein. The agreement entitles AgPlenus
        to an upfront payment, which was received on March 2024, ongoing
        research funding, milestone payments, and royalties based on future
        product sales. Bayer will have the exclusive license for developing and
        commercializing products resulting from this collaboration.
    --  In March, 2024, AgPlenus announced achieving a milestone under its
        existing collaboration with Corteva to develop new herbicides through a
        novel mode of action, APCO12, discovered by AgPlenus. The next phase of
        this collaboration will focus on optimizing the herbicide candidates
        towards a commercial-level product.

Financial Highlights:

Cash Position: As of March 31, 2024, Evogene held consolidated cash, cash equivalents, and short-term bank deposits of approximately $26.6 million, compared to approximately $31.1 million as of December 31, 2023. The consolidated cash usage during the Q1 2024 was approximately $4.5 million. Excluding Lavie Bio and Biomica, Evogene and its other subsidiaries used approximately $3.4 million in cash. Projected cash usage for 2024, excluding Lavie Bio and Biomica, is expected to be around $8.0 million, marking a notable 36% decrease from approximately $12.5 million in 2023.

Revenue: Revenues for the first quarter of 2024 were approximately $4.2 million, a significant increase from approximately $0.6 million in the same period the previous year. This growth was primarily driven by revenues recognized from Lavie Bio's licensing agreement with Corteva and AgPlenus's new collaboration with Bayer. Evogene anticipates continued revenue growth in 2024 compared to the previous year, mainly in the second half of 2024 based on Casterra's forecast for seed-order supply.

R&D Expenses: Research and development expenses for the first quarter of 2024 were stable at approximately $4.8 million, net of non-refundable grants, consistent with the same period in the previous year.

Sales and Marketing Expenses: These expenses increased to $992 thousand in the first quarter of 2024 compared to $800 thousand in the same period of the previous year. The increase was driven by heightened sales and marketing activities for Casterra's elite seed varieties and Lavie Bio's first commercial product, Yalos((TM)).

General and Administrative Expenses: General and administrative expenses rose to approximately $1.7 million in the first quarter of 2024, compared to approximately $1.5 million in the same period of the previous year, mainly due to non-cash compensation for subsidiary CEOs.

Other Expenses: The decision to cease Canonic's operations resulted in recording other expenses of approximately $0.5 million, mainly due to impairment of fixed assets.

Operating Loss: The operating loss for the first quarter of 2024 was approximately $4.1 million, a decrease from $6.8 million in the same period of the previous year, mainly due to increased revenues.

Financing Income: Financing income net for the first quarter of 2024 was $241 thousand, compared to financing expenses net of $230 thousand in the same period of the previous year. This improvement was primarily due to increased interest income and revaluation of convertible SAFE.

Net Loss: The net loss for the first quarter of 2024 was approximately $3.8 million, compared to approximately $7.0 million in the same period last year. The $3.2 million decrease in net loss was primarily due to increased revenues and financial income, partially offset by the one-time $519 thousand other expenses related to ceasing Canonic's operations.

For the financial tables click here.

Conference Call & Webcast Details: Thursday, May 23, 2024. 9:00 AM EST 4:00 PM IDT
To join the Zoom conference, please register in advance here

Or join via audio
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Webinar ID: 871 1216 5951

Webcast & Presentation link available at:
https://evogene.com/investor-relations/

About Evogene Ltd.

Evogene Ltd. (Nasdaq: EVGN, TASE: EVGN) is a computational biology company leveraging big data and artificial intelligence, aiming to revolutionize the development of life-science based products by utilizing cutting-edge technologies to increase the probability of success while reducing development time and cost.

Evogene established three unique tech-engines - MicroBoost AI, ChemPass AI and GeneRator AI. Each tech-engine is focused on the discovery and development of products based on one of the following core components: microbes (MicroBoost AI), small molecules (ChemPass AI), and genetic elements (GeneRator AI).

Evogene uses its tech-engines to develop products through strategic partnerships and collaborations, and its four subsidiaries including:

    --  Biomica Ltd. (www.biomicamed.com)  - developing and advancing novel
        microbiome-based therapeutics to treat human disorders powered by
        MicroBoost AI;
    --  Lavie Bio (www.lavie-bio.com) - developing and commercially advancing,
        microbiome based ag-biologicals powered by MicroBoost AI;
    --  AgPlenus Ltd. (www.agplenus.com) - developing next generation
        ag-chemicals for effective and sustainable crop protection powered by
        ChemPass AI;
    --  Casterra Ag (www.casterra.co) - developing and marketing superior castor
        seed varieties producing high yield and high-grade oil content, on an
        industrial scale for the biofuel and other industries powered by
        GeneRator AI.

For more information, please visit: www.evogene.com.

Forward-Looking Statements

This press release contains "forward-looking statements" relating to future events. These statements may be identified by words such as "may", "could", "expects", "hopes" "intends", "anticipates", "plans", "believes", "scheduled", "estimates", "demonstrates" or words of similar meaning. For example, Evogene and its subsidiaries are using forward-looking statements in this press release when they discuss Evogene's strategy, its anticipated growth in 2024, projected 2024 cash usage, expected annualized savings from ceasing Canonic's operations, Casterra's ability to supply all existing purchase orders by the end of 2024 and providing additional inventory, the success of Biomica's microbiome-based drugs in future trials, the results of the validation trials of Lavie Bio with Bayer, the anticipated revenues from sale of Yalos, Ag Plenus receipt of milestone and royalty payments from Bayer and Ag Plenus ability to reach commercial-level products in its project with Corteva. Such statements are based on current expectations, estimates, projections and assumptions, describe opinions about future events, involve certain risks and uncertainties which are difficult to predict and are not guarantees of future performance. Therefore, actual future results, performance, or achievements of Evogene and its subsidiaries may differ materially from what is expressed or implied by such forward-looking statements due to a variety of factors, many of which are beyond the control of Evogene and its subsidiaries, including, without limitation, the current war between Israel, Hamas and Hezbollah and any worsening of the situation in Israel such as further mobilizations or escalation in the northern border of Israel, and those risk factors contained in Evogene's reports filed with the applicable securities authority. In addition, Evogene and its subsidiaries rely, and expect to continue to rely, on third parties to conduct certain activities, such as their field trials and pre-clinical studies, and if these third parties do not successfully carry out their contractual duties, comply with regulatory requirements or meet expected deadlines, Evogene and its subsidiaries may experience significant delays in the conduct of their activities. Evogene and its subsidiaries disclaim any obligation or commitment to update these forward-looking statements to reflect future events or developments or changes in expectations, estimates, projections and assumptions.



            
              CONSOLIDATED INTERIM STATEMENTS OF FINANCIAL POSITION



            
              U.S. dollars in thousands




                                                                              As of March As of December
                                                                                   31,           31,


                                                                                     2024            2023


                                                                               Unaudited      Audited



            
              
                CURRENT ASSETS:



            Cash and cash equivalents                                            $11,915         $20,772



            S
            hort-term bank deposits                                     14,698          10,291



            Trade receivables                                                        539             357



            Other receivables and prepaid expenses                                 3,154           2,973



            Inventories                                                              716              76




                                                                                   31,022          34,469



            
              
                LONG-TERM ASSETS:



            Long-term deposits and other receivables                                  26              28



            Investment accounted for using the equity method                         133



            Right-of-use-assets                                                      879             980



            Property, plant and equipment, net                                     1,796           2,455



            Intangible assets, net                                                12,924          13,169




                                                                                   15,758          16,632




                                                                                  $46,780         $51,101



            
              
                CURRENT LIABILITIES:



            Trade payables                                                        $1,041          $1,785



            Employees and payroll accruals                                         2,432           2,537



            Lease liability                                                          715             853



            Liabilities in respect of government grants                              561             388



            Deferred revenues and other advances                                     416             362



            Other payables                                                           964           1,019




                                                                                    6,129           6,944



            
              
                LONG-TERM LIABILITIES:



            Lease liability                                                          286             285



            Liabilities in respect of government grants                            4,237           4,426



            Deferred revenues and other advances                                     402             393



            Convertible SAFE                                                      10,343          10,368




                                                                                   15,268          15,472



            
              
                SHAREHOLDERS' EQUITY:



            Ordinary shares of NIS 0.02 par value:                                   286             286


            Authorized - 150,000,000 ordinary shares; Issued and
    outstanding - 50,623,278 shares as of March 31, 2024 and
    50,584,888 shares as of December 31, 2023



            Share premium and other capital reserve                              269,452         269,353



            Accumulated deficit                                                (261,449)      (257,586)





            Equity attributable to equity holders of the Company                   8,289          12,053





            Non-controlling interests                                             17,094          16,632





            Total equity                                                          25,383          28,685




                                                                                  $46,780         $51,101



              
                CONSOLIDATED INTERIM STATEMENTS OF PROFIT OR LOSS



              
                U.S. dollars in thousands (except share and per share amounts)




                                                                                                                 Three months ended                       Year ended

                                                                                                                 March 31,                      December 31,


                                                                                                 2024       2023                           2023


                                                                                                                 Unaudited                         Audited





              Revenues                                                                        $4,190       $641                         $5,640



              Cost of revenues                                                                   310        322                          1,692





              Gross profit                                                                     3,880        319                          3,948





              Operating expenses:





              Research and development, net                                                    4,801      4,800                         20,777



              Sales and marketing                                                                992        800                          3,611



              General and administrative                                                       1,654      1,515                          6,068



              O
              ther expenses                                                          519





              Total operating expenses, net                                                    7,966      7,115                         30,456





              Operating loss                                                                 (4,086)   (6,796)                      (26,508)





              Financing income                                                                   407        308                          1,486



              Financing expenses                                                               (166)     (538)                         (965)





              Financing income (expenses), net                                                   241      (230)                           521





              Loss before taxes on income                                                    (3,845)   (7,026)                      (25,987)



              Tax benefit                                                                                 (45)                          (33)





              Loss                                                                          $(3,845)  $(6,981)                     $(25,954)





              Attributable to:



              Equity holders of the Company                                                  (3,863)   (6,271)                      (23,879)



              Non-controlling interests                                                           18      (710)                       (2,075)




                                                                                             $(3,845)  $(6,981)                     $(25,954)




                                                                                              $(0.08)   $(0.15)                       $(0.52)


              Basic and diluted loss per share, attributable to
    equity holders of the Company





              Weighted average number of shares used in                                   50,622,922 41,489,001                     45,685,619
    computing basic and diluted loss per share



       
                CONSOLIDATED INTERIM STATEMENTS OF CASH FLOWS



       
                U.S. dollars in thousands




                                                                                                         Three months ended                      Year ended

                                                                                                         March 31,                     December 31,


                                                                                          2024      2023                        2023


                                                                                                         Unaudited                        Audited





       
                
                  Cash flows from operating activities:

    ---




       Loss                                                                          $(3,845) $(6,981)                     $(25,954)





       Adjustments to reconcile loss to net cash used in operating activities:





       Adjustments to the profit or loss items:





       Depreciation                                                                       426       401                         1,641



       Amortization of intangible assets                                                  245       240                           971



       Share-based compensation                                                           539       418                         1,877



       Revaluation of convertible SAFE                                                   (25)      194                           254



       Net financing 
              income                                                  (194)     (54)                         (666)



       L
              oss (
              gain) from sale and impairment of property, plant



       and equipment                                                                      519      (26)                          (26)



       Tax benefit                                                                                (45)                          (33)




                                                                                         1,510     1,128                         4,018





       Changes in asset and liability items:





       Decrease (increase) in trade receivables                                         (182)       98                            (9)



       Increase in other receivables                                                    (179)    (291)                       (1,445)



       Decrease (increase) in inventories                                               (640)     (25)                          490



       Decrease in deferred taxes                                                                   94                            94



       Increase (decrease) in trade payables                                            (685)      121                           742



       Increase (decrease) in employees and payroll accruals                            (105)       55                           550



       Decrease in other payables                                                        (61)    (553)                         (534)



       Increase (decrease) in deferred revenues and other advances                       (71)        8                          (288)




                                                                                       (1,923)    (493)                         (400)





       Cash received (paid) during the year for:





       Interest received                                                                  171       138                           905



       Interest paid                                                                     (23)     (36)                         (115)



       Taxes paid                                                                                                               (31)





       Net cash used in operating activities                                         $(4,110) $(6,244)                     $(21,577)



              
                CONSOLIDATED INTERIM STATEMENTS OF CASH FLOWS



              
                U.S. dollars in thousands




                                                                                                                   Three months ended             Year ended


                                                          
              
                March 31, December 31,


                                                                                                            2024     2023                    2023


                                                                                                                   Unaudited              Audited





              
                
                  Cash flows from investing activities:

    ---




              Purchase of property, plant and equipment                                                   $(141)  $(359)                $(785)



              Proceeds from sale of marketable securities                                                           637                 6,924



              Purchase of marketable securities                                                                                         (503)



              Proceeds from sale of property, plant and equipment                                            10       26                    26



              Investment in bank deposits, net                                                          (4,231)                      (10,200)





              Net cash provided by (used in) investing activities                                       (4,362)     304                (4,538)





              
                
                  Cash flows from financing activities:

    ---




              Issuance of a subsidiary preferred shares to non-controlling interests                                                   9,523



              Proceeds from issuance of ordinary shares, net of issuance expenses                             3      268                 8,449



              Repayment of lease liability                                                                (231)   (206)                 (836)



              Proceeds from government grants                                                                        26                 1,089



              Repayment of government grants                                                              (139)    (35)                  (73)





               Net cash provided by (used in) financing activities                                        (367)      53                18,152







               Exchange rate differences - cash and cash equivalent balances                                 (18)    (93)                  (245)





              Decrease in cash and cash equivalents                                                       (8,857) (5,980)                (8,208)





              Cash and cash equivalents at the beginning of the period                                     20,772   28,980                  28,980





              Cash and cash equivalents at the end of the period                                          $11,915  $23,000                 $20,772







              
                
                  Significant non-cash activities

    ---


              Acquisition of property, plant and equipment                                                    $22      $69                     $81





              Investment in equity-accounted investee with corresponding                                      133
    deferred revenues





              Increase of right-of-use asset recognized with corresponding                                   $130      $71                    $194
    lease liability

Evogene Investors Relations Contact:
Rachel Pomerantz Gerber, Head of Investor Relations at Evogene
Email: rachel.pomerantz@evogene.com
Tel: +972-8-9311901

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